Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.
Disabil Rehabil. 2022 Nov;44(23):7096-7105. doi: 10.1080/09638288.2021.1981468. Epub 2021 Oct 5.
This study aimed to identify mental health, physical health, demographic and disease characteristics relating to work productivity in people with multiple sclerosis (MS).
In this cross-sectional study, 236 employed people with MS (median age = 42 years, 78.8% female) underwent neurological and neuropsychological assessments. Additionally, they completed questionnaires inquiring about work productivity (presenteeism: reduced productivity while working, and absenteeism: loss of productivity due to absence from work), mental and physical health, demographic and disease characteristics. Multiple linear and logistic regression analyses were performed with presenteeism and absenteeism as dependent variables, respectively.
A model with mental and physical health factors significantly predicted presenteeism (11,202) = 11.33, < 0.001, = 0.38; a higher cognitive ( < 0.001) and physical impact ( = 0.042) of fatigue were associated with more presenteeism. A model with only mental health factors significantly predicted absenteeism; (11)=37.72, < 0.001, with = 0.27 (Nagelkerke) and = 0.16 (Cox and Snell). Specifically, we observed that more symptoms of depression ( = 0.041) and a higher cognitive impact of fatigue ( = 0.011) were significantly associated with more absenteeism.
In people with MS, both cognitive and physical impact of fatigue are positively related to presenteeism, while symptoms of depression and cognitive impact of fatigue are positively related to absenteeism.Implications for rehabilitationMultiple sclerosis (MS) affects people of working age, significantly interfering with work productivity.Higher cognitive and physical impact of fatigue were associated with more presenteeism in workers with MS.A higher cognitive impact of fatigue and more depressive symptoms were associated with absenteeism in workers with MS.Occupational and healthcare professionals should be aware of the impact of both physical and mental health on work productivity in workers with MS.
本研究旨在确定与多发性硬化症（MS）患者工作生产力相关的心理健康、身体健康、人口统计学和疾病特征。
在这项横断面研究中，236 名在职 MS 患者（中位年龄=42 岁，78.8%为女性）接受了神经学和神经心理学评估。此外，他们还完成了调查问卷，询问工作生产力（生产力下降：工作时生产力下降，缺勤：因缺勤而导致生产力损失）、心理健康和身体健康、人口统计学和疾病特征。分别以生产力下降和缺勤为因变量，进行多元线性和逻辑回归分析。
一个包含心理健康和身体健康因素的模型显著预测了生产力下降（11,202）=11.33， < 0.001， = 0.38；疲劳的认知（ < 0.001）和身体影响（ = 0.042）与更多的生产力下降相关。一个仅包含心理健康因素的模型显著预测了缺勤；（11）=37.72， < 0.001， = 0.27（Nagelkerke）和 = 0.16（Cox 和 Snell）。具体而言，我们观察到更多的抑郁症状（ = 0.041）和疲劳的认知影响（ = 0.011）与更多的缺勤显著相关。
在多发性硬化症患者中，疲劳的认知和身体影响均与生产力下降呈正相关，而抑郁症状和疲劳的认知影响与缺勤呈正相关。
多发性硬化症（MS）影响处于工作年龄的人群，严重干扰工作生产力。疲劳的认知和身体影响越大，MS 患者的生产力下降越严重。疲劳的认知影响越大和抑郁症状越多，MS 患者的缺勤越严重。职业和医疗保健专业人员应意识到身体和心理健康对 MS 患者工作生产力的影响。
