State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Department of Ophthalmology, Columbia University Medical Center, New York, NY, USA.
Asia Pac J Ophthalmol (Phila). 2021 Oct 1;10(6):548-552. doi: 10.1097/APO.0000000000000438. Print 2021 Nov-Dec.
Trabeculectomy with adjunctive use of Mitomycin C (MMC) has been a benchmark for glaucoma filtration surgery for decades. However, there are many variations in the ways that the sponges soaked with MMC are applied during the trabeculectomy surgery. We herein describe our way of placing the MMC-soaked sponges to improve the safety and efficacy of the trabeculectomy. The sponges are placed vertically and posteriorly with the long side of the sponge perpendicular to the limbus, not parallel. This will reduce the size of the conjunctival wound at the limbus to preserve more virgin conjunctiva that can be used for repeated trabeculectomy when needed. This will also facilitate a more posteriorly directed flow of aqueous drainage that, in turn, may increase the success rate of the trabeculectomy. We have obtained encouraging results in our practice, and further large-scale randomized studies seem warranted.
几十年来,小梁切除术联合丝裂霉素 C(MMC)的应用一直是青光眼滤过性手术的基准。然而,在小梁切除术手术中,MMC 浸泡海绵的应用方式有很多变化。我们在此描述了我们放置 MMC 浸泡海绵的方法,以提高小梁切除术的安全性和有效性。海绵垂直放置于后部,海绵的长边垂直于角膜缘,而不是平行于角膜缘。这将减少角膜缘处结膜伤口的大小,从而保留更多可用于在需要时进行重复小梁切除术的原始结膜。这也将促进更向后的房水引流,从而可能提高小梁切除术的成功率。我们在实践中取得了令人鼓舞的结果,似乎有必要进行更大规模的随机研究。