COPD Foundation, Miami, Florida.
Department of Medicine, Columbia University, New York, New York.
Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L983-L987. doi: 10.1152/ajplung.00400.2021. Epub 2021 Oct 6.
World COPD Day raises awareness about chronic obstructive pulmonary disease (COPD). COPD accounts for over 150,000 US deaths per year. A major challenge is that COPD receives only a fraction of the research funding provided to other major diseases. Control of COPD is dependent on developing new approaches to diagnose the disease earlier with a recognition of either pre-COPD or established COPD based on symptoms, lung structural change and/or loss of lung function that occurs before meeting long established criteria for a population-based definition of obstruction. Optimization of current therapies improves lung function, exercise capacity, quality of life, and survival. New pathways of disease progression are being identified creating new opportunities for development of therapies that could stop or cure this disease.
世界慢性阻塞性肺疾病日提高了人们对慢性阻塞性肺疾病（COPD）的认识。COPD 每年导致超过 150000 人死亡。一个主要的挑战是，COPD 仅获得了其他主要疾病研究资金的一小部分。COPD 的控制依赖于开发新的方法来更早地诊断疾病，根据症状、肺结构变化和/或在满足基于人群的阻塞定义的长期既定标准之前发生的肺功能丧失，识别出预 COPD 或已建立的 COPD。优化现有治疗方法可改善肺功能、运动能力、生活质量和生存率。正在确定疾病进展的新途径，为开发可阻止或治愈这种疾病的治疗方法创造了新的机会。
