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[中国阜宁县50岁及以上2型糖尿病患者未矫正屈光不正的流行病学:江苏糖尿病眼病研究]

[Epidemiology of uncorrected refractive errors in type 2 diabetics aged 50 and above in Funing County, China: the Jiangsu Diabetic Eye Study].

作者信息

Yang M, Liu B H, Sun D J, Liang C K, Wang S Y, Zhu R R

机构信息

Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong 226001, China.

Funing Shizhuang Eye Hospital, Yancheng 224000, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2021 Oct 11;57(10):757-765. doi: 10.3760/cma.j.cn112142-20201010-00650.

DOI:10.3760/cma.j.cn112142-20201010-00650
PMID:34619946
Abstract

To estimate the prevalence of uncorrected refractive errors among people aged 50 years and above in Funing county, Jiangsu province. Randomly cluster sampling was used in selecting individuals aged ≥50 years in 82 clusters from Funing County Center for Disease Prevention and Control. Uncorrected refractive error was defined as an improvement of at least 2 lines in best corrected visual acuity compared with presenting visual acuity in the better eye. The mean±standard deviation was used to describe the continuous data, and the rate or composition ratio was used to represent the classified data. Univariate and multivariate logistic regression analyses were used to analyze the prevalence of uncorrected refractive errors in different ages, genders, educational levels, durations of diabetes and levels of glycosylated hemoglobin. Statistical significance was defined as <0.05. A total of 2 067 persons were enumerated, and 1910 (92.4%) participants were in the statistical analyses. The prevalence of uncorrected refractive error was 25.63%. The prevalence of uncorrected refractive error for myopia only, hyperopia only, astigmatism only, myopia with astigmatism and hyperopia with astigmatism was 72.55% (37/51), 46.77% (58/124), 17.81% (13/73), 63.95% (94/147) and 51.98% (100/194), respectively. The results showed that the older age, level of glycosylated hemoglobin, myopia and lens state were the independent influencing factors of uncorrected refractive error. The odds ratio () for people aged 70 to<80 years and ≥80 years was 1.81 and 1.90, respectively, with statistical significance compared to people younger than 60 years. Compared with the level of glycosylated hemoglobin less than 5.6%, the with glycosylated hemoglobin from7.1% to 8.0% and more than 10% was 1.84 (0.05) and 1.82 (0.05), respectively. The of myopia, low myopia, moderate myopia and high myopia was 2.98 (0.01), 6.94 (0.01), 42.43 (0.01) and 77.85 (0.01), respectively. The of opacity of the eye lens was 7.60 (<0.01). Uncorrected refractive error is one of the important causes of visual impairment in diabetic patients aged 50 and above in Funing county, Jiangsu province; the important influencing factors were age, glycosylated hemoglobin concentration, myopia and lens status. Relevant health departments should popularize the eye health for diabetic patients and conduct regular optometry and fundus examination. .

摘要

为估算江苏省阜宁县50岁及以上人群中未矫正屈光不正的患病率。采用随机整群抽样方法,从阜宁县疾病预防控制中心选取82个群组中年龄≥50岁的个体。未矫正屈光不正定义为最佳矫正视力较较好眼的就诊视力至少提高2行。采用均数±标准差描述连续性数据,率或构成比表示分类数据。采用单因素和多因素logistic回归分析不同年龄、性别、文化程度、糖尿病病程及糖化血红蛋白水平人群中未矫正屈光不正的患病率。统计学显著性定义为<0.05。共纳入2067人,1910名(92.4%)参与者纳入统计分析。未矫正屈光不正的患病率为25.63%。单纯近视、单纯远视、单纯散光、近视合并散光以及远视合并散光的未矫正屈光不正患病率分别为72.55%(37/51)、46.77%(58/124)、17.81%(13/73)、63.95%(94/147)和51.98%(100/194)。结果显示,年龄较大、糖化血红蛋白水平、近视和晶状体状态是未矫正屈光不正的独立影响因素。70至<80岁及≥80岁人群的比值比(OR)分别为1.81和1.90,与60岁以下人群相比具有统计学显著性。与糖化血红蛋白水平<5.6%相比,糖化血红蛋白水平为7.1%至8.0%及>10%的OR分别为1.84(P<0.05)和1.82(P<0.05)。近视、低度近视、中度近视和高度近视的OR分别为2.98(P<0.01)、6.94(P<0.01)、42.43(P<0.01)和77.85(P<0.01)。晶状体混浊的OR为7.60(P<0.01)。未矫正屈光不正是江苏省阜宁县50岁及以上糖尿病患者视力损害的重要原因之一;重要影响因素为年龄、糖化血红蛋白浓度、近视和晶状体状态。相关卫生部门应普及糖尿病患者的眼健康知识,并定期进行验光和眼底检查。

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