Scientific and Medical Affairs, Abbott Nutrition, 2900 Easton Square Place, Columbus, OH, 43219 USA.
Duke University School of Medicine, Department of Anesthesiology and Surgery, Center for Perioperative Organ Protection (CPOP), DUMC, Box 3094 Mail # 41, 2301 Erwin Road, 5692 HAFS, Durham, NC, 27710 USA.
Clin Nutr ESPEN. 2021 Oct;45:1-8. doi: 10.1016/j.clnesp.2021.08.023. Epub 2021 Sep 3.
Currently, there is a lack of consensus on the provision of preoperative carbohydrate loading in patients with type 2 diabetes mellitus (T2DM) due to theoretical concerns including the possibility of delayed gastric emptying, perioperative hyperglycemia, and poor surgical outcomes. This narrative review summarizes the accumulating evidence on preoperative carbohydrate loading in this population and whether these concerns are supported by preliminary evidence. In general, the available research suggests that carbohydrate loading may be implemented in those with T2DM without increased risk for intra- and postoperative hyperglycemia or surgical complications. However, there is strong justification for future research to definitively study this highly debated and timely topic. Ultimately, the inclusion of preoperative carbohydrate loading for surgical patients with DM should be guided by the surgical team's clinical judgment and individualized based on patient needs and characteristics.
目前,由于理论上的担忧,包括胃排空延迟、围手术期高血糖和手术结果不佳的可能性,对于 2 型糖尿病(T2DM)患者是否提供术前碳水化合物负荷仍存在共识。本叙述性综述总结了该人群中术前碳水化合物负荷的累积证据,以及这些担忧是否得到初步证据的支持。一般来说,现有研究表明,在 T2DM 患者中实施碳水化合物负荷可能不会增加术中及术后高血糖或手术并发症的风险。然而,未来的研究有充分的理由来明确研究这个备受争议和及时的话题。最终,对于糖尿病手术患者是否纳入术前碳水化合物负荷应根据手术团队的临床判断,并根据患者的需求和特点进行个体化决定。