Department of Dermatology and Hair Transplant, Dr Amit Kerure Skin Clinic, Navi Mumbai, India.
Department of Dermatology, BJ Govt Medical College and Sassoon Hospital, Pune, India.
Dermatol Ther. 2021 Nov;34(6):e15156. doi: 10.1111/dth.15156. Epub 2021 Oct 15.
Alopecia areata (AA) is a non-scarring autoimmune type of alopecia. Hair transplantation in AA is not practiced as the implanted follicular grafts might be destroyed due to underlying autoimmune pathology. A biopsy proven 28 year old male patient of AA presented to us with an 8-year history of a hairless patch over the beard area. He underwent many treatments by other dermatologist with oral, topical, and intralesional immunosuppressants, which curtailed his disease progression but failed to re-grow hair. Biopsy during his visit revealed absence of inflammatory infiltrates and empty hair tracts replaced by fibrotic tracts. Follicular unit extraction (FUE) was done successfully after counseling the patient about the controversial role of hair transplant surgery in AA. Hair growth was achieved within 6 months with no recurrence during 1-year follow up. FUE can be opted for long-standing and clinically stable cases of AA; histopathology and dermoscopy being the guiding lights in determining the disease inactivity.
斑秃(AA)是一种非瘢痕性自身免疫性脱发。由于潜在的自身免疫病理,AA 患者不进行毛发移植,因为植入的毛囊移植物可能会被破坏。一位 28 岁的男性斑秃患者,8 年前出现胡须区域无毛斑块,曾接受过其他皮肤科医生的多种治疗,包括口服、局部和皮损内免疫抑制剂,这些治疗虽然控制了疾病进展,但未能使头发再生。就诊时的活检显示无炎症浸润,空的毛囊道被纤维性道取代。在对患者进行毛发移植手术在 AA 中的作用存在争议的咨询后,成功地进行了毛囊单位提取(FUE)。6 个月内实现了毛发生长,1 年随访期间无复发。FUE 可用于长期和临床稳定的 AA 病例;组织病理学和皮肤镜检查是确定疾病静止的指导因素。