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《胡须斑秃:文献回顾》。

Alopecia Areata of the Beard: A Review of the Literature.

机构信息

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL, 33136, USA.

出版信息

Am J Clin Dermatol. 2017 Dec;18(6):789-796. doi: 10.1007/s40257-017-0297-6.

Abstract

Alopecia areata (AA) is a T-cell mediated autoimmune disorder in which inflammatory cells attack the hair follicle, resulting in round, well-circumscribed patches of noncicatricial hair loss in normal appearing skin. AA affecting the beard area is well known and is referred to as AA of the beard (BAA) or AA barbae when involvement is limited exclusively to the beard. BAA has been documented in a select number of studies. We review the literature and discuss the clinical features, epidemiology, diagnosis, and treatment of BAA. Clinical presentation of BAA can vary and manifest as single small areas of hair loss, multiple small or large simultaneous focuses, or total hair loss. Most patients are middle-aged males with focal patches of round or oval hair loss, mostly localized along the jawline. Patches are characteristically well circumscribed and smooth with white hair present at the periphery. Dermoscopic features of BAA include yellow dots, broken hair, and short vellus hairs. BAA may be associated with other autoimmune disorders, including atopic dermatitis, vitiligo, and psoriasis. Many treatment modalities are available for BAA, and selection of a therapy depends on several factors, including disease activity, extent of area affected, duration of disease, and age of the patient. Topical corticosteroids are most commonly used as initial treatment, followed by intralesional steroids. Other therapeutic modalities are discussed.

摘要

斑秃(AA)是一种 T 细胞介导的自身免疫性疾病,其中炎症细胞攻击毛囊,导致正常皮肤出现圆形、边界清晰的非瘢痕性脱发斑块。影响胡须区域的 AA 是众所周知的,当仅限于胡须时,称为 AA 的胡须(BAA)或 AA 胡须。BAA 在少数研究中已有记录。我们回顾了文献,讨论了 BAA 的临床特征、流行病学、诊断和治疗。BAA 的临床表现可能不同,表现为单个小面积脱发、多个小或大的同时焦点或全部脱发。大多数患者为中年男性,有局灶性圆形或椭圆形脱发斑,主要位于下颌线附近。斑块的特征是边界清晰、光滑,周围有白发。BAA 的皮肤镜特征包括黄色斑点、断发和短毳毛。BAA 可能与其他自身免疫性疾病有关,包括特应性皮炎、白癜风和银屑病。BAA 有多种治疗方法,治疗选择取决于多种因素,包括疾病活动度、受累面积大小、疾病持续时间和患者年龄。局部皮质类固醇最常用于初始治疗,其次是皮损内类固醇。讨论了其他治疗方法。

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