Akita Kazuki, Kumakura Yasutomo, Nakajima Emi, Ishiguro Hiroki, Iijima Tetsuya
Department of Anesthesiology, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi, Japan.
Center of Medical team, University of Yamanashi Hospital, 1110 Shimokato, Chuo City, Yamanashi, Japan.
JA Clin Rep. 2021 Oct 9;7(1):75. doi: 10.1186/s40981-021-00477-1.
Vertebral compression fractures can cause severe back pain. Although many types of analgesics and interventional treatments are available, they are sometimes ineffective in mitigating the pain. We encountered a case where clonazepam was effective for the management of severe low back pain caused by lumbar vertebral compression fractures.
A 44-year-old male was diagnosed with multiple myeloma and had vertebral compression fractures of the first and second lumbar vertebrae. He had been suffering from severe low back pain on movement with muscle spasm and pain-associated anxiety. We considered this breakthrough low back pain to be caused by facet joint pain; thus, we prescribed clonazepam as a muscle relaxant and anxiolytic. Following this treatment, the intractable breakthrough pain was dramatically relieved.
Clonazepam, which has both muscle relaxant and anxiolytic effects, might be helpful in mitigating pain, associated anxiety, and muscle spasms due to vertebral compression fractures.
椎体压缩性骨折可导致严重的背痛。尽管有多种类型的镇痛药和介入治疗方法，但它们有时在减轻疼痛方面效果不佳。我们遇到了一例氯硝西泮对治疗腰椎椎体压缩性骨折引起的严重腰痛有效的病例。
一名44岁男性被诊断为多发性骨髓瘤，第一和第二腰椎椎体发生压缩性骨折。他因运动时严重的腰痛伴有肌肉痉挛和疼痛相关焦虑而饱受折磨。我们认为这种突破性腰痛是由小关节疼痛引起的；因此，我们开具了氯硝西泮作为肌肉松弛剂和抗焦虑药。经过这种治疗，顽固性突破性疼痛得到了显著缓解。
具有肌肉松弛和抗焦虑作用的氯硝西泮可能有助于减轻椎体压缩性骨折引起的疼痛、相关焦虑和肌肉痉挛。
