Seidel M, Gorynia I
Psychiatr Neurol Med Psychol (Leipz). 1986 May;38(5):265-74.
In a female patient with Gilles-de-la Tourette syndrome (GTS) the clinical improvement during drug therapy of haloperidol and clomipramine was proved with the help of a polygraphic method (simultaneous recording of different electrophysiological and vegetative parameters). Before intensifying therapy symptoms of vegetative irritation, motoric discharge patterns with high amplitude in correlation with movements and permanent activity with low amplitude even in a state of external motoric rest were found. After intensifying therapy vegetative stabilization and ceasing of any electrical activity in the EMG could be demonstrated. It is concluded that the effects of therapy in GTS may be checked and quantified by means of polygraphic methods.
在一名患有 Gilles - de - la 图雷特综合征(GTS)的女性患者中,借助多导记录法(同时记录不同的电生理和植物神经参数)证实了氟哌啶醇和氯米帕明药物治疗期间的临床改善情况。在强化治疗前,发现了植物神经刺激症状、与运动相关的高振幅运动放电模式以及即使在外部运动静止状态下仍存在的低振幅持续活动。强化治疗后,可证明植物神经功能稳定且肌电图中任何电活动均停止。得出的结论是,GTS 的治疗效果可以通过多导记录法进行检查和量化。