Division of Pediatric Neurology, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, Lemoyne, Pennsylvania.
Pediatr Neurol. 2021 Dec;125:40-47. doi: 10.1016/j.pediatrneurol.2021.08.008. Epub 2021 Sep 6.
Fasciculations are the most common form of spontaneous muscle contraction. They frequently occur in healthy individuals. However, there are a minority of situations that fasciculations are observed in association with specific neurologic disorders. Publications concerning the evaluation of pediatric patients experiencing fasciculations are limited. These children may undergo invasive or expensive diagnostic investigations that are unnecessary. Moreover, without careful consideration of differential diagnoses, rare neuromuscular disorders that present with fasciculations in the pediatric age group can be under-recognized by pediatric neurologists. This review examines the most important pediatric disorders presenting with fasciculations and other spontaneous muscle contractions to guide pediatric neurologists in evaluating these children.
肌束震颤是最常见的自发性肌肉收缩形式。它们经常发生在健康个体中。然而,也有少数情况下肌束震颤与特定的神经障碍有关。关于评估出现肌束震颤的儿科患者的文献有限。这些儿童可能需要进行不必要的侵入性或昂贵的诊断性检查。此外,如果不仔细考虑鉴别诊断,儿科神经病学家可能会忽略在儿科年龄段出现肌束震颤的罕见神经肌肉疾病。本综述检查了最重要的儿科疾病,这些疾病表现为肌束震颤和其他自发性肌肉收缩,以指导儿科神经病学家评估这些儿童。