Mega James, O'Brien Victoria, Hammond Nicholas, Aeum Judy, Bunch Kristen
Department of Radiology, Tripler Army Medical Center, 1 Jarrett White Rd. Honolulu, HI 96859 USA.
Department of Obstetrics and Gynecology, Tripler Army Medical Center, 1 Jarrett White Rd. Honolulu, HI 96859 USA.
Radiol Case Rep. 2021 Oct 2;16(12):3675-3679. doi: 10.1016/j.radcr.2021.08.061. eCollection 2021 Dec.
Primary and disseminated lymphoma of the female reproductive tract are rare types of lymphoma. However, in the setting of solid organ transplant, recipients have an approximately doubled risk of acquiring and dying from malignancy. Multiple treatment modalities are available for post-transplant lymphoproliferative diseases (PTLD), including chemotherapy, radiotherapy, surgery, and immunosuppression radiotherapy. We report a case of a 61-year-old female with multifocal nodal diffuse large B-cell lymphoma and a history of a renal transplant secondary to IgA nephropathy who developed metastatic diffuse large B-cell lymphoma to the uterus. While the baseline incidence of PTLD is elevated when compared with lymphoma in the general population, metastatic uterine lymphoma is rare. Awareness of reproductive organ involvement by lymphomas and increased malignancy risk in organ transplant patients are important considerations for diagnostic evaluation, including radiologic assessment.
女性生殖道原发性和播散性淋巴瘤是罕见的淋巴瘤类型。然而，在实体器官移植的情况下，接受者患恶性肿瘤并死于恶性肿瘤的风险大约会增加一倍。移植后淋巴增殖性疾病（PTLD）有多种治疗方式，包括化疗、放疗、手术和免疫抑制放疗。我们报告一例61岁女性，患有多灶性淋巴结弥漫性大B细胞淋巴瘤，有因IgA肾病继发肾移植病史，发生了子宫转移性弥漫性大B细胞淋巴瘤。虽然与普通人群中的淋巴瘤相比，PTLD的基线发病率有所升高，但转移性子宫淋巴瘤却很罕见。认识到淋巴瘤对生殖器官的累及以及器官移植患者恶性肿瘤风险增加，对于包括放射学评估在内的诊断性评估来说是重要的考虑因素。
