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COVID-19大流行时代的心脏移植:谵妄、移植后抑郁及访客限制;联络与住院身心治疗的作用——一例病例报告

Heart transplantation in the era of COVID-19 pandemic: delirium, post-transplant depression, and visitor restrictions; the role of liaison and inpatient psychosomatic treatment-a case report.

作者信息

Sadlonova Monika, Gerecke Birgit, Herrmann-Lingen Christoph, Kutschka Ingo

机构信息

Department of Cardiovascular and Thoracic Surgery, University of Göttingen Medical Center, Robert-Koch-Str. 40, 37075 Göttingen, Germany.

Department of Psychosomatic Medicine and Psychotherapy, University of Göttingen Medical Center, Robert-Koch-Str. 40, 37075 Göttingen, Germany.

出版信息

Eur Heart J Case Rep. 2021 Sep 9;5(10):ytab355. doi: 10.1093/ehjcr/ytab355. eCollection 2021 Oct.

Abstract

BACKGROUND

Heart transplant recipients show a high risk of developing major depression with an increased risk of post-transplant morbidity and mortality. Heart transplant specialists and patients face unprecedented challenges during the COVID-19 pandemic, which have enormous clinical implications such as the increased risk of COVID-19 as well as visitor restrictions with social isolation during the post-transplant inpatient treatment.

CASE SUMMARY

We present a case of a 64-year-old woman with end-stage heart failure caused by non-compaction cardiomyopathy who received an orthotopic heart transplant (OHT) without any intra-operative complications. Post-operatively, she showed acute psychotic symptoms in the intensive care unit (ICU) with improvement after switching intravenous tacrolimus treatment to an oral intake. Furthermore, the patient developed severe depressive symptoms with malnutrition and had a prolonged hospitalization. Standard medical care was complemented by intensive psychocardiological treatment to overcome the crisis.

CONCLUSION

High complexity of the post-transplant management after OHT underlines the importance of multidisciplinary teamwork, involving heart transplant specialists and allied mental health professionals. This collaboration led to an excellent long-term result. Facing the COVID-19 pandemic, the hospital visitor policies may be scrutinized, carefully looking at the role of social isolation, post-operative experience in the ICU, and medical complications after OHT.

摘要

背景

心脏移植受者发生重度抑郁症的风险较高,移植后发病和死亡风险也会增加。在新冠疫情期间,心脏移植专家和患者面临着前所未有的挑战,这些挑战具有巨大的临床意义,例如感染新冠病毒的风险增加,以及移植后住院治疗期间因访客限制导致的社交隔离。

病例摘要

我们报告一例64岁女性患者,因非致密化心肌病导致终末期心力衰竭,接受了原位心脏移植(OHT),术中无任何并发症。术后,她在重症监护病房(ICU)出现急性精神病症状,将静脉注射他克莫司治疗改为口服后症状有所改善。此外,患者出现严重抑郁症状并伴有营养不良,住院时间延长。通过强化心理心脏治疗来补充标准医疗护理,以度过危机。

结论

OHT术后移植管理的高度复杂性凸显了多学科团队合作的重要性,团队成员包括心脏移植专家和相关心理健康专业人员。这种合作带来了出色的长期效果。面对新冠疫情,医院的访客政策可能需要审视,仔细考量社交隔离的作用、在ICU的术后经历以及OHT后的医疗并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53a5/8497879/583ba04f20ff/ytab355f1.jpg

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