Radiation Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Radiation Oncology Department, Osakidetza/Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, Barakaldo, Spain.
Clin Transl Oncol. 2022 Feb;24(2):215-226. doi: 10.1007/s12094-021-02695-6. Epub 2021 Oct 11.
The use of stereotactic body radiation therapy (SBRT) to treat non-spine bone metastases (NSBM) is becoming increasingly common in clinical practice. The clinical advantages of SBRT include good pain control and high local control rates, although only limited data are available. The Spanish Society of Radiation Oncology (SEOR) SBRT group recently convened a task force of experts in the field to address key questions related to SBRT for NSBM, including treatment indications, planning, techniques, and dose fractionation. The task force reviewed the available literature to develop evidence-based recommendations for the safe application of NSBM SBRT and to standardize and optimize SBRT processes. The present document provides a comprehensive analysis of the available data, including ongoing clinical trials and controversies, providing clinically applicable recommendations.
立体定向体部放射治疗(SBRT)在非脊柱骨转移(NSBM)的治疗中越来越普遍,在临床实践中得到了广泛应用。SBRT 的临床优势包括良好的疼痛控制和较高的局部控制率,尽管可用的数据有限。西班牙放射肿瘤学会(SEOR)SBRT 小组最近召集了该领域的专家工作组,针对 NSBM 的 SBRT 相关关键问题,包括治疗适应证、计划、技术和剂量分割进行了探讨。工作组对现有文献进行了回顾,旨在为 NSBM SBRT 的安全应用提供循证推荐,并使 SBRT 流程标准化和优化。本文件对现有数据进行了全面分析,包括正在进行的临床试验和争议,为临床应用提供了切实可行的推荐。