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[因滥用笑气继发的颈椎脊髓病:一种新发疾病]

[Cervical myelopathy secondary to recreational nitrous oxide use: an emergent pathology].

作者信息

Le Borgne Pierrick, Colin Jules, Bilbault Pascal, Andres Emmanuel, Lorenzo-Villalba Noel

机构信息

Service des Urgences, Hôpitaux Universitaires de Strasbourg, Francia.

Service de Médecine Interne, Diabète et Maladies Métaboliques, Hôpitaux Universitaires de Strasbourg, Francia.

出版信息

Medicina (B Aires). 2021;81(5):840-842.

PMID:34633959
Abstract

We describe the case of a 27-year-old female patient who presented to the emergency ward with hypoesthesia and paresthesia developing over the last two months, initially in both feet and progressing to the knees in a few days without associated gait disorders. Dystonia in the thumb and index finger of both hands was noted. Blood tests including toxic drugs were negative. The spinal magnetic resonance imaging was consistent with (C3-C5) myelopathy or myelitis without other abnormalities suggestive of systemic diseases. The biochemical and bacteriological analysis of the cerebrospinal fluid was normal. Because of these findings, the patient was re-interviewed to determine the consumption of unusual drugs, and nitrous oxide consumption was referred. The patient was admitted for further studies, which confirmed the diagnosis.

摘要

我们描述了一名27岁女性患者的病例,该患者在过去两个月出现感觉减退和感觉异常,最初累及双足,数天内进展至双膝,无相关步态障碍。同时发现双手拇指和示指出现肌张力障碍。包括毒品检测在内的血液检查均为阴性。脊柱磁共振成像显示符合(C3 - C5)脊髓病或脊髓炎,无其他提示全身性疾病的异常表现。脑脊液的生化和细菌学分析正常。基于这些发现,对患者进行了再次询问以确定是否使用了特殊药物,发现其使用过氧化亚氮。患者入院接受进一步检查,最终确诊。

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