Dupree W B, Enzinger F M
Cancer. 1986 Nov 1;58(9):2103-9. doi: 10.1002/1097-0142(19861101)58:9<2103::aid-cncr2820580923>3.0.co;2-c.
Twenty-one cases of a benign fibro-osseous pseudotumor occurring in the soft tissues of the digits are described. They affected mostly young adults. Twenty of the 21 cases involved the soft tissues of the fingers, especially the proximal portions of the index or middle finger, and one case involved the toe. Microscopically these tumor-like lesions closely resembled myositis ossificans, but unlike this process they involved chiefly the subcutaneous tissue and adjacent fibrous structures and were marked by an irregular multinodular growth pattern without the typical zoning of myositis ossificans. Because of the focal hypercellularity, cellular atypia and increased mitotic activity six of the cases were initially interpreted as being parosteal or extraskeletal osteosarcoma. Follow-up information indicates that this lesion behaves in a nonaggressive fashion and is curable by complete local excision.
本文描述了21例发生于手指软组织的良性纤维骨假瘤。它们主要累及年轻人。21例中有20例累及手指软组织，尤其是示指或中指近端，1例累及足趾。显微镜下，这些肿瘤样病变与骨化性肌炎极为相似，但与该病变不同的是，它们主要累及皮下组织和相邻纤维结构，其特征为不规则的多结节生长模式，无骨化性肌炎典型的分层现象。由于局灶性细胞增多、细胞异型性及有丝分裂活性增加，6例最初被诊断为骨旁骨肉瘤或骨外骨肉瘤。随访资料表明，该病变呈非侵袭性，完整局部切除可治愈。
