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富血小板血浆在舟状骨骨折不愈合中的作用-病例系列。

Role of platelet rich plasma in fracture non-union of scaphoid - Case series.

机构信息

The Indus Hospital,Karachi, Pakistan.

Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong.

出版信息

J Pak Med Assoc. 2021 Aug;71(Suppl 5)(8):S103-S106.

PMID:34634028
Abstract

This case series of 4 patients was studied at Queen Mary Hospital, Hong Kong from 2007 to 2011 to evaluate the clinical and radiological outcome of scaphoid fracture non-union treated with Open reduction and internal fixation ORIF supplemented with Bone Graft (BG) from iliac crest and Platelet Rich Plasma PRP. The purpose was to achieve union with pain free adequate range of movement. Patients presenting with scaphoid fracture non-union were included in our study. Total 4 patients with an average age of 35±7.7 years (range 31 to 47 years) and mean follow-up of 21.75±14.97 months, (range 05 months to 3.5 years) were included. All patients achieved union with pain free Range of motion of wrist as well as thumb. We recommend open reduction and internal fixation with bone graft along with platelets rich plasma for non-union of scaphoid.

摘要

本病例系列研究共纳入 4 例患者,均来自于 2007 年至 2011 年期间的中国香港玛丽医院,旨在评估切开复位内固定术(ORIF)联合髂嵴骨移植(BG)和富血小板血浆(PRP)治疗舟状骨骨折不愈合的临床和影像学结果。该研究的目的是实现无痛、足够活动范围的愈合。本研究纳入了所有符合舟状骨骨折不愈合标准的患者。共有 4 名患者,平均年龄 35±7.7 岁(范围 31 至 47 岁),平均随访时间为 21.75±14.97 个月(范围 05 个月至 3.5 年)。所有患者均实现了无痛、腕关节和拇指活动范围正常的愈合。我们建议对舟状骨骨折不愈合患者采用切开复位内固定术联合骨移植和富含血小板的血浆进行治疗。

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引用本文的文献

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Front Surg. 2025 May 12;12:1454101. doi: 10.3389/fsurg.2025.1454101. eCollection 2025.
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Platelet-rich plasma enhances rib fracture strength and callus formation in vivo.富含血小板血浆可增强体内肋骨骨折强度及骨痂形成。
J Trauma Acute Care Surg. 2024 Dec 1;97(6):884-890. doi: 10.1097/TA.0000000000004441. Epub 2024 Sep 6.
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Comparative effectiveness of three treatment options for slade and dodds grade III-IV scaphoid nonunion: a retrospective study.
斯莱德和多德斯 III-IV 级舟骨骨不连三种治疗方案的疗效比较:一项回顾性研究。
BMC Musculoskelet Disord. 2023 Mar 17;24(1):204. doi: 10.1186/s12891-023-06320-1.