一位重塑抗病毒药物行业的药物化学家：约翰·查尔斯·马丁（1951-2021 年）。
A medicinal chemist who reshaped the antiviral drug industry: John Charles Martin (1951-2021).
机构信息
Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha, China.
KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Leuven, Belgium.
出版信息
Med Res Rev. 2022 Mar;42(2):647-653. doi: 10.1002/med.21858. Epub 2021 Oct 12.
John Charles Martin should be remembered as a visionary medicinal chemist who was involved in the coinvention, development, or management of many FDA-approved antiviral drugs such as ganciclovir, stavudine, didanosine, cidofovir, oseltamivir, adefovir dipivoxil, tenofovir disoproxil fumarate, tenofovir alafenamide, sofosbuvir, and remdesivir.
约翰·查尔斯·马丁（John Charles Martin）应该被铭记为一位有远见的药物化学家，他参与了许多 FDA 批准的抗病毒药物的共同发明、开发或管理，如更昔洛韦、司他夫定、去羟肌苷、西多福韦、奥司他韦、阿德福韦酯、富马酸替诺福韦二吡呋酯、替诺福韦艾拉酚胺、索非布韦和瑞德西韦。
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