Clínica Luis Oliva, Tenerife, Spain.
Clínica Renacimiento, Las Palmas de Gran Canaria, Spain.
J Cosmet Dermatol. 2022 Mar;21(3):962-969. doi: 10.1111/jocd.14523. Epub 2021 Oct 12.
With aging, there is a decrease in the volume of facial fat compartments, which can be restored using injectable biodegradable fillers.
The objective of this study was to assess the efficacy and safety of an ultrasound-guided transoral injection versus the traditional percutaneous approach for cheek volumization with hyaluronic acid.
PATIENTS/METHODS: This is a pilot, single-center, comparative, prospective study conducted in Spain in which the hemifaces were randomized to receive an injection with each technique, and the duration of follow-up was 1 year. Results were assessed using the GAIS and the procedure satisfaction survey. The degree of pain experienced was evaluated using a VAS for pain.
This study included 20 women with a mean age of 45.3 years (SD 5.1, range of 38-53). No significant differences were observed in esthetic improvement scores or in the satisfaction surveys. There were significant differences in the transoral approach assessment at V3 (p = 0.0362) and in both procedures at V6 (p = 0.0026) between patients and evaluators. Of all patients, 55% (n = 11/20) reported less pain with the transoral approach, and 15% (n = 3/20) did not perceive pain with any techniques. No side effects different than those expected were observed, and they all resolved without the need for treatment.
The transoral approach for cheek volumization with hyaluronic acid was shown as a safe, effective technique that provides more comfort and minor sensation of pain than the traditional percutaneous approach but with equivalent esthetic outcomes.
随着年龄的增长，面部脂肪隔体积减少，可以通过注射可生物降解的填充剂来恢复。
本研究旨在评估超声引导经口内注射与传统经皮注射用于透明质酸丰颊的疗效和安全性。
患者/方法：这是一项在西班牙进行的单中心、前瞻性、随机、对照的试点研究，将半侧脸随机分配接受两种技术的注射，随访时间为 1 年。使用 GAIS 和程序满意度调查评估结果。使用疼痛视觉模拟量表（VAS）评估疼痛程度。
本研究纳入 20 名年龄 45.3 岁（标准差 5.1，范围 38-53）的女性。在美学改善评分或满意度调查中，两种技术均未观察到显著差异。在 V3 时，经口内入路评估（p=0.0362）和 V6 时两种方法评估（p=0.0026）在患者和评估者之间存在显著差异。所有患者中，55%（n=11/20）报告经口内入路疼痛较轻，15%（n=3/20）在任何技术下均无疼痛感觉。未观察到与预期不同的不良反应，所有不良反应均无需治疗即可缓解。
经口内注射透明质酸丰颊是一种安全有效的技术，与传统经皮入路相比，提供了更多的舒适度和较小的疼痛感觉，但具有相同的美学效果。
