University of Louisville School of Public Health and Information Sciences, 485 E Gray St, Louisville, KY, 40202, USA.
Kent School of Social Work at the University of Louisville, Louisville, KY, USA.
Arch Sex Behav. 2021 Oct;50(7):2933-2941. doi: 10.1007/s10508-021-01974-1. Epub 2021 Oct 12.
Pre-exposure prophylaxis (PrEP) is a biomedical HIV prevention strategy with potential to reduce racial HIV disparities. However, African-Americans have not received the benefits of PrEP to the same extent as other groups. The theory of planned behavior (TPB) was employed to explain intentions to use PrEP among a sample of African-Americans (age 18-29) in Louisville, Kentucky. Data were derived from the Afya Project, a study examining PrEP-focused HIV prevention for African-American young adults. The sample was developed through respondent-driven sampling and participants (N = 181) completed audio computer-assisted self-interviews assessing demographics and TPB variables. Analysis of variance was used to examine relationships between demographics and PrEP intentions. Linear regressions determined associations between control beliefs, attitudes, norms, and PrEP use intentions. Confidence in using PrEP (p ≤ .0001), perceived HIV risk (p ≤ 0.05), perceived likelihood of acquiring HIV (p ≤ 0.05), and positive norms around PrEP (p ≤ 0.05) were significantly associated with PrEP use intentions. Findings can inform interventions to advance PrEP as a HIV prevention option for African-American populations at higher risk of contracting HIV.
暴露前预防 (PrEP) 是一种具有减少种族间 HIV 差异潜力的生物医学 HIV 预防策略。然而，非裔美国人并没有像其他群体那样受益于 PrEP。本研究采用计划行为理论 (TPB) 来解释肯塔基州路易斯维尔市的非裔美国人（18-29 岁）对使用 PrEP 的意图。数据来自 Afya 项目，该项目研究了针对非裔美国年轻成年人的以 PrEP 为重点的 HIV 预防措施。该样本通过应答者驱动抽样产生，参与者（N=181）完成了评估人口统计数据和 TPB 变量的音频计算机辅助自我访谈。方差分析用于检验人口统计学变量与 PrEP 意图之间的关系。线性回归确定了控制信念、态度、规范与 PrEP 使用意图之间的关联。使用 PrEP 的信心（p≤0.0001）、对 HIV 风险的感知（p≤0.05）、感染 HIV 的可能性感知（p≤0.05）和 PrEP 规范的积极感知（p≤0.05）与 PrEP 使用意图显著相关。研究结果可以为针对 HIV 感染风险较高的非裔美国人的干预措施提供信息，以推进 PrEP 作为 HIV 预防选择。
