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头颈部癌症放化疗患者的营养干预:荷兰头颈部肿瘤中心的现行实践。

Nutritional interventions in patients with head and neck cancer undergoing chemoradiotherapy: Current practice at the Dutch Head and Neck Oncology centres.

机构信息

Department of Dietetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.

出版信息

Eur J Cancer Care (Engl). 2022 Jan;31(1):e13518. doi: 10.1111/ecc.13518. Epub 2021 Oct 12.

DOI:10.1111/ecc.13518
PMID:34637563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9285387/
Abstract

OBJECTIVE

To assess variations in nutritional interventions during chemoradiotherapy (CRT) among the Dutch Head and Neck Oncology centres (HNOCs).

METHODS

An online questionnaire about nutritional interventions and dietetic practices was sent to 14 oncology dietitians of the HNOCs.

RESULTS

The response rate was 93%. The number of scheduled dietetic consultations varied from two to seven during CRT. Most centres (77%) reported using a gastrostomy for tube feeding in the majority of patients. Gastrostomies were placed prophylactically upon indication (39%) or in all patients (15%), reactive (15%), or both (31%). For calculating energy requirements, 54% of the dietitians used the Food and Agriculture Organization/World Health Organization and United Nations University (FAO/WHO/UNU) formula and 77% uses 1.2-1.5 g/kg body weight for calculating protein requirements. Almost half of the centres (46%) reported to remove the gastrostomy between 8 and 12 weeks after CR. Most centres (92%) reported to end dietary treatment within 6 months after CRT.

CONCLUSION

This study shows substantial variation in dietetic practice, especially in the use of a gastrostomy for tube feeding, between the HNOCs. There is a need for concise dietetic guidelines.

摘要

目的

评估荷兰头颈部肿瘤治疗中心(HNOC)在放化疗(CRT)期间营养干预措施的差异。

方法

向 14 名 HNOC 的肿瘤营养师在线发送了一份关于营养干预措施和饮食实践的问卷。

结果

应答率为 93%。在 CRT 期间,安排的饮食咨询次数从两次到七次不等。大多数中心(77%)报告在大多数患者中使用胃造口术进行管饲。胃造口术预防性放置(39%)或全部患者(15%)、反应性(15%)或两者兼而有之(31%)。在计算能量需求方面,54%的营养师使用了粮农组织/世界卫生组织和联合国大学(FAO/WHO/UNU)公式,77%的营养师使用 1.2-1.5 g/kg 体重来计算蛋白质需求。近一半的中心(46%)报告在 CRT 后 8 至 12 周之间取出胃造口管。大多数中心(92%)报告在 CRT 后 6 个月内结束饮食治疗。

结论

本研究表明,HNOC 之间的饮食实践存在很大差异,尤其是在使用胃造口术进行管饲方面。需要制定简明的饮食指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c996/9285387/d7bf8173c447/ECC-31-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c996/9285387/d7bf8173c447/ECC-31-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c996/9285387/d7bf8173c447/ECC-31-0-g001.jpg

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Nutr Clin Pract. 2020 Dec;35(6):1129-1137. doi: 10.1002/ncp.10476. Epub 2020 Mar 5.
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Prediction model for tube feeding dependency during chemoradiotherapy for at least four weeks in head and neck cancer patients: A tool for prophylactic gastrostomy decision making.头颈部癌症患者放化疗至少四周期间管饲依赖预测模型:预防性胃造口术决策的工具。
Clin Nutr. 2020 Aug;39(8):2600-2608. doi: 10.1016/j.clnu.2019.11.033. Epub 2019 Dec 3.
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GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community.
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J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):207-217. doi: 10.1002/jcsm.12383.
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Low muscle mass is associated with early termination of chemotherapy related to toxicity in patients with head and neck cancer.肌肉质量低与头颈部癌症患者因毒性而提前终止化疗有关。
Clin Nutr. 2020 Feb;39(2):501-509. doi: 10.1016/j.clnu.2019.02.029. Epub 2019 Feb 22.
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From reactive to proactive tube feeding during chemoradiotherapy for head and neck cancer: A clinical prediction model-based approach.从头颈部癌症放化疗期间的反应性管饲到主动性管饲:一种基于临床预测模型的方法。
Oral Oncol. 2019 Jan;88:172-179. doi: 10.1016/j.oraloncology.2018.11.031. Epub 2018 Dec 7.
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