Genet Lucie, De Luca Daniele
Division of Pediatrics and Neonatal Critical Care, "A.Béclère" Medical Center, Paris Saclay University Hospitals, APHP, Paris, France.
Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France.
Cardiol Young. 2022 Jun;32(6):996-997. doi: 10.1017/S1047951121004157. Epub 2021 Oct 13.
Persistent pulmonary hypertension of the neonate can cause acute and life-threatening hypoxia, but preterm neonates are not suitable candidate to extra-corporeal life support. We report the unique case of an extremely preterm neonates with life-threatening persistent pulmonary hypertension refractory to triple vasodilator therapy (nitric oxide, iloprost, and bosentan), which has been successfully treated with the addition of adenosine continuous infusion.
新生儿持续性肺动脉高压可导致急性且危及生命的缺氧，但早产儿并非体外生命支持的合适人选。我们报告了一例极为早产的新生儿的独特病例，该患儿患有危及生命的持续性肺动脉高压，对三联血管扩张剂治疗（一氧化氮、伊洛前列素和波生坦）无效，通过加用腺苷持续输注成功治愈。
