腺苷可逆转对三联血管扩张剂治疗无效的危及生命的新生儿持续性肺动脉高压。
Adenosine reverses life-threatening persistent pulmonary hypertension of the neonate refractory to triple vasodilator therapy.
作者信息
Genet Lucie, De Luca Daniele
机构信息
Division of Pediatrics and Neonatal Critical Care, "A.Béclère" Medical Center, Paris Saclay University Hospitals, APHP, Paris, France.
Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France.
出版信息
Cardiol Young. 2022 Jun;32(6):996-997. doi: 10.1017/S1047951121004157. Epub 2021 Oct 13.
Persistent pulmonary hypertension of the neonate can cause acute and life-threatening hypoxia, but preterm neonates are not suitable candidate to extra-corporeal life support. We report the unique case of an extremely preterm neonates with life-threatening persistent pulmonary hypertension refractory to triple vasodilator therapy (nitric oxide, iloprost, and bosentan), which has been successfully treated with the addition of adenosine continuous infusion.
新生儿持续性肺动脉高压可导致急性且危及生命的缺氧，但早产儿并非体外生命支持的合适人选。我们报告了一例极为早产的新生儿的独特病例，该患儿患有危及生命的持续性肺动脉高压，对三联血管扩张剂治疗（一氧化氮、伊洛前列素和波生坦）无效，通过加用腺苷持续输注成功治愈。
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