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一名年轻非洲女性的肉瘤样肝细胞癌

Sarcomatoid hepatocellular carcinoma in a young African female.

作者信息

Sadiq Abid M, Mjemmas Minael G, Sadiq Adnan M, Nkya Gilbert Z

机构信息

Department of Internal Medicine, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Kilimanjaro Christian Medical University College, Moshi, Tanzania.

出版信息

SAGE Open Med Case Rep. 2021 Oct 9;9:2050313X211052452. doi: 10.1177/2050313X211052452. eCollection 2021.

Abstract

Sarcomatoid hepatocellular carcinoma is a rare primary malignant liver cancer. The pathogenesis is unclear; however, the risk factors may be similar to that of conventional hepatocellular carcinoma. We present an 18-year-old female who was admitted due to generalized tonic-clonic convulsions. On examination, we palpated a large non-tender mass in the right upper quadrant. An abdominal computed tomography identified it as hepatocellular carcinoma, and spindle-shaped cells were seen on histopathology. She was counseled on her prognosis but opted for local herbal medications rather than chemotherapy, but unfortunately passed away. We present a rare subtype of hepatocellular carcinoma in a young female which is commonly seen in males above the age of 50 years, and despite its grade and stage, overall survival is poor.

摘要

肉瘤样肝细胞癌是一种罕见的原发性恶性肝癌。其发病机制尚不清楚;然而,危险因素可能与传统肝细胞癌相似。我们报告一名18岁女性,因全身强直阵挛性惊厥入院。检查时,我们在右上腹触及一个大的无压痛肿块。腹部计算机断层扫描将其诊断为肝细胞癌,组织病理学检查可见梭形细胞。我们向她告知了预后情况,但她选择了当地的草药治疗而非化疗,不幸的是她去世了。我们报告了一名年轻女性中罕见的肝细胞癌亚型,这种癌症常见于50岁以上的男性,无论其分级和分期如何,总体生存率都很低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/8504208/be904ad81fdc/10.1177_2050313X211052452-fig1.jpg

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