[亚胺培南/西司他丁钠在儿科领域的临床评估]
[Clinical evaluation of imipenem/cilastatin sodium in the pediatric field].
作者信息
Hirosawa H, Hoshina H, Morikawa Y, Ichihashi H
出版信息
Jpn J Antibiot. 1986 Jul;39(7):1733-44.
PMID:3464776
Abstract
Imipenem/cilastatin sodium (MK-0787/MK-0791) was evaluated for its safety and efficacy in 7 pediatric patients with infections. The clinical efficacy ratio was 100 percent. No side effect was observed except for elevations of S-GOT and S-GPT and eosinophilia in 1 patient. It may be considered that MK-0787/MK-0791 is a safe and useful antibiotic for the treatment of pediatric infections.
摘要
对7例感染患儿评估了亚胺培南/西司他丁钠（MK - 0787/MK - 0791）的安全性和疗效。临床有效率为100%。除1例患者出现谷草转氨酶和谷丙转氨酶升高以及嗜酸性粒细胞增多外，未观察到副作用。可以认为MK - 0787/MK - 0791是治疗小儿感染的一种安全有效的抗生素。
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