急性淋巴细胞白血病患者中发现 HLA 抗原 CW3 与无法解释的高皮质素结合球蛋白水平相关，但在其父母、兄弟姐妹及后代中未发现此情况。
HLA antigen CW3 combined with unexplained high transcortin levels is found in patients with acute lymphoblastic leukemia but not in their parents, sibs and offspring.
作者信息
de Moor P, Louwagie A
出版信息
J Steroid Biochem. 1986 Oct;25(4):489-90. doi: 10.1016/0022-4731(86)90392-4.
PMID:3464809
Abstract
ALL patients with an unexplained high transcortin level (greater than or equal to 3 SD above the normal mean) have a higher incidence of HLA antigen Cw3 than patients with a lower transcortin level. Although both factors are inheritable, their combination occurs only rarely in the family members of these patients.
摘要
所有不明原因的高皮质素结合球蛋白水平（高于正常均值3个标准差及以上）的患者，其HLA抗原Cw3的发生率高于皮质素结合球蛋白水平较低的患者。尽管这两个因素都是可遗传的，但它们的组合在这些患者的家庭成员中很少出现。
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