Beck J D
Monatsschr Kinderheilkd. 1986 Aug;134(8):547-9.
After pretreatment with anthracyclines, a boy entered a second complete remission of an acute myeloid leukemia lasting already for 16 months following chemotherapy with Aclacinomycin A combined with Etoposide, Cytosine Arabinoside and Thioguanine. The newly developed Aclacinomycin A was well tolerated. Presumably there is no cross resistance between Aclacinomycin A and the anthracyclines, the latter being in use for the therapy of leukemias since some time.
在用蒽环类药物预处理后，一名男孩进入急性髓性白血病的第二次完全缓解期，在用阿克拉霉素A联合依托泊苷、阿糖胞苷和硫鸟嘌呤进行化疗后，缓解期已持续16个月。新研发的阿克拉霉素A耐受性良好。推测阿克拉霉素A与蒽环类药物之间不存在交叉耐药性，蒽环类药物用于白血病治疗已有一段时间。
