Rosevear S K, Liggins G C
N Z Med J. 1986 May 28;99(802):356-7.
Platelet number, mean platelet volume (MPV) and platelet distribution width (PDW) were measured in 55 women admitted consecutively during four months from January-April 1984 with pregnancy-induced hypertension. The criteria for diagnosis were a sustained diastolic blood pressure greater than 90 mmHg during the first 24 h after admission, normal blood pressure recordings in the first trimester and a plasma urate value exceeding 0.34 mmol/l. The values were grouped according to gestation length and compared with those in a control group of 96 women of similar gestation lengths who were normotensive. Both MPV and PDW were significantly greater in the hypertensive group whereas platelet numbers did not differ. It is concluded that measurement of MPV and PDW is a useful diagnostic criterion of pregnancy-induced hypertension.
对1984年1月至4月连续四个月收治的55例妊娠高血压综合征患者测定了血小板计数、平均血小板体积（MPV）和血小板分布宽度（PDW）。诊断标准为入院后最初24小时内舒张压持续高于90mmHg，孕早期血压记录正常且血浆尿酸值超过0.34mmol/L。根据妊娠时长对这些值进行分组，并与96例妊娠时长相似的血压正常女性组成的对照组进行比较。高血压组的MPV和PDW均显著更高，而血小板计数无差异。结论是，MPV和PDW的测定是妊娠高血压综合征的一项有用诊断标准。
