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颅内结核瘤:一例临床、影像学及病理特征的病例报告

Intracranial tuberculomas: A case report of clinical, radiological, and pathological characteristics.

作者信息

Alharbi Ahoud, Khairy Sami, Al Sufiani Fahd, Alkhani Ahmed

机构信息

Division of Neurosurgery, Department of Surgery, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Division of Neurosurgery, Department of Surgery, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2021 Nov;88:106477. doi: 10.1016/j.ijscr.2021.106477. Epub 2021 Oct 8.

Abstract

BACKGROUND

Intracranial tuberculomas are uncommon yet devastating forms of extrapulmonary tuberculosis with a high mortality rate and morbidity risk. A high level of suspicion is required for a prompt diagnosis and treatment.

CASE DESCRIPTION

A 67-year-old male, medically free, presented at the Emergency Department with a 1-day history of nausea and vomiting, and a 15-day history of imbalance and dizziness. Radiological imaging demonstrated right well-defined ring-enhancing lesions. He underwent a sup-occipital craniotomy with lesion resection. The diagnosis of an intracranial tuberculoma was confirmed histopathologically. Anti-tuberculosis therapy was prescribed, and the patient was discharged with mild cerebellar dysfunction.

DISCUSSION

Intracranial tuberculomas have a high rate of mortality and morbidity. It is critical to consider tuberculoma in the differential diagnosis of intracranial lesions with such clinico-radiological characteristics, especially in developing countries.

CONCLUSION

In this article, we are reporting an interesting case with multiple intracranial tuberculomas with an extensive review of the literature.

摘要

背景

颅内结核瘤是肺外结核的罕见但具有破坏性的形式,死亡率和发病风险高。需要高度怀疑才能及时诊断和治疗。

病例描述

一名67岁男性,无病史,因1天的恶心呕吐病史以及15天的平衡失调和头晕病史就诊于急诊科。影像学检查显示右侧边界清晰的环形强化病灶。他接受了枕下开颅病灶切除术。组织病理学确诊为颅内结核瘤。给予抗结核治疗,患者出院时伴有轻度小脑功能障碍。

讨论

颅内结核瘤的死亡率和发病率很高。在具有此类临床放射学特征的颅内病变的鉴别诊断中考虑结核瘤至关重要,尤其是在发展中国家。

结论

在本文中,我们报告了一例有趣的多发性颅内结核瘤病例,并对文献进行了广泛综述。

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