通过共振拉曼光谱法证明甲氧沙林（吡咯并喹啉醌）是牛血浆胺氧化酶中的辅因子。
Evidence for methoxatin (pyrroloquinolinequinone) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy.
作者信息
Moog R S, McGuirl M A, Cote C E, Dooley D M
出版信息
Proc Natl Acad Sci U S A. 1986 Nov;83(22):8435-9. doi: 10.1073/pnas.83.22.8435.
Abstract
Resonance Raman spectra of the 2,4-dinitrophenylhydrazine derivatives of bovine plasma amine oxidase [amine:oxygen oxidoreductase (deaminating) (copper-containing), EC 1.4.3.6] have been measured. Detailed comparisons to the spectra of the corresponding derivatives of methoxatin (pyrroloquinolinequinone), pyridoxal, and other aldehydes and diones provide further evidence that covalently bound methoxatin or a closely similar derivative is the organic cofactor in copper-containing amine oxidases.
摘要
已测定牛血浆胺氧化酶[胺：氧氧化还原酶（脱氨基）（含铜），EC 1.4.3.6]的2,4-二硝基苯肼衍生物的共振拉曼光谱。与甲氧喋呤（吡咯并喹啉醌）、吡哆醛以及其他醛类和二酮的相应衍生物的光谱进行详细比较，进一步证明共价结合的甲氧喋呤或紧密相似的衍生物是含铜胺氧化酶中的有机辅因子。
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