Wu Y F, Zhang X Y, Ren S, Yu Y X, Chang C Q
Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing Key Laboratory of Sports Injuries, Beijing 100191, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2021 Oct 18;53(5):843-849. doi: 10.19723/j.issn.1671-167X.2021.05.006.
To investigate the correlation between the quadriceps cross-sectional area (CSA) and quadriceps muscle volume (QMV) at different horizontal levels from the upper edge of the patella, and to determine the best observation position.
Thigh magnetic resonance imaging (MRI) images of 22 Chinese young men [age: (29±6) years] with anterior cruciate ligament (ACL) rupture were examined. The CSA was measured at 18, 15, and 12 cm above the upper edge of the pate-lla (denoted by CSA-18, CSA-15 and CSA-12 respectively), and the QMV and CSA were determined by semiautomatic segmentation. A curve model was established to estimate QMV. Bland-Altman analysis was performed to determine the confidence limits of the volumes.
On the unaffected side, the mean QMV was (1 944.45±323.77) cm. The quadriceps CSA at the upper edge of the patella at 18, 15, and 12 cm was (80.80±12.16) cm, (77.53±12.03) cm, and (72.68±10.51) cm, respectively. The coefficients of determination (), ascertained using curve estimation models, for the 3 positions were 0.819, 0.755, and 0.684 ( < 0.001), and the standard deviations of the volume estimated value (SEE) were 7.4%, 8.7%, and 9.8%. The fitting equations of the three horizontal positions were all good, but the fitting degree of CSA-18 was the highest. The Bland-Altman scatter plot showed that the arithmetic means of the QMV at 18, 15 and 12 cm from the upper edge of the patella 0.8 cm, -1.1 cm, and 0.9 cm and 95% limits of agreement (LoA) were (-268.8, 270.5), (-315.2, 313.1), and (-355.7, 357.5), respectively. The estimated QMV was in good agreement with the measured value. The difference between the estimated CSA-18 and measured values was the smallest. The results on the affected side were consistent.
The correlation between QMV and CSA in the young men with the upper edge of patella as baseline was reliable and consistent. Among them, CSA-18 had the highest correlation with the QMV. However, different observation sites could be selected for different injuries of the quadriceps.
探讨髌骨上缘不同水平处股四头肌横截面积（CSA）与股四头肌体积（QMV）之间的相关性，并确定最佳观察位置。
对22名中国年轻男性[年龄：（29±6）岁]前交叉韧带（ACL）断裂患者的大腿磁共振成像（MRI）图像进行检查。在髌骨上缘上方18、15和12 cm处测量CSA（分别记为CSA-18、CSA-15和CSA-12），并通过半自动分割确定QMV和CSA。建立曲线模型以估计QMV。进行Bland-Altman分析以确定体积的置信限。
在未受伤侧，平均QMV为（1 944.45±323.77）cm³。髌骨上缘18、15和12 cm处的股四头肌CSA分别为（80.80±12.16）cm²、（77.53±12.03）cm²和（72.68±10.51）cm²。使用曲线估计模型确定的3个位置的决定系数（R²）分别为0.819、0.755和0.684（P<0.001），体积估计值的标准误差（SEE）分别为7.4%、8.7%和9.8%。三个水平位置的拟合方程均良好，但CSA-18的拟合度最高。Bland-Altman散点图显示，距髌骨上缘18、15和12 cm处QMV的算术平均值分别为0.8 cm、-1.1 cm和0.9 cm，95%一致性界限（LoA）分别为（-268.8，270.5）、（-315.2，313.1）和（-355.7，357.5）。估计的QMV与测量值吻合良好。估计的CSA-18与测量值之间的差异最小。受伤侧的结果一致。
以髌骨上缘为基线的年轻男性中，QMV与CSA之间的相关性可靠且一致。其中，CSA-18与QMV的相关性最高。然而，对于股四头肌的不同损伤情况，可选择不同的观察部位。
