Department of Medicine, University of Washington, Seattle, Washington, USA.
HIV/STD Program, Public Health-Seattle and King County, Seattle, Washington, USA.
J Correct Health Care. 2021 Dec;27(4):259-264. doi: 10.1089/jchc.19.07.0056. Epub 2021 Oct 14.
The objective of this study was to compare tuberculosis (TB) screening results before and after implementation of a stratified testing strategy screening pilot study, incorporating interferon gamma release assay (IGRA) and tuberculin skin test (TST), based on country of origin. In 2015, the Washington State Department of Corrections began screening people born outside of the United States for TB with IGRA, while U.S.-born people continued screening by TST. Of 405 (75%) foreign-born men screened with IGRA, 403 had valid test results and IGRA screening positivity was 10.4% ( = 42). In contrast, among 5,940 primarily U.S-born men screened with TST, 24 (0.4%) were positive. Overall positivity was 1.05%, similar to TST-only positivity in 2013 (1.05%) and 2014 (0.85%). Incorporating IGRA screening among foreign-born persons was feasible in this state prison system.
本研究的目的是比较在实施基于原籍国的分层检测策略筛查试点研究（包括干扰素-γ释放试验（IGRA）和结核菌素皮肤试验（TST））前后的结核病（TB）筛查结果。2015 年，华盛顿州惩教署开始对出生于美国境外的人进行 IGRA 筛查，而美国出生的人继续进行 TST 筛查。在接受 IGRA 筛查的 405 名（75%）外国出生男性中，有 403 名有有效检测结果，IGRA 筛查阳性率为 10.4%（ = 42）。相比之下，在接受 TST 筛查的 5940 名主要为美国出生的男性中，有 24 名（0.4%）呈阳性。总体阳性率为 1.05%，与 2013 年（1.05%）和 2014 年（0.85%）仅进行 TST 筛查的阳性率相似。在该州监狱系统中，对外国出生者进行 IGRA 筛查是可行的。
