Indian Council of Medical Research-Regional Medical Research Centre (RMRC), Gorakhpur, Uttar Pradesh, 273013, India.
Indian Council of Medical Research-National Institute of Virology (ICMR-NIV), Pune, Maharashtra, 411021, India.
J Travel Med. 2021 Dec 29;28(8). doi: 10.1093/jtm/taab166.
The evidence for effectiveness of heterologous priming of COVID-19 vaccine is very limited. Here, we studied eighteen participants who received heterologous vaccination regimen of AstraZeneca’s ChAdOx1-nCov-19 followed by inactivated whole virion BBV152. Heterologous group participant doesn’t report any adverse event following immunization and demonstrated high humoral and neutralizing antibody response.
针对 COVID-19 疫苗异源初免的有效性证据非常有限。在此,我们研究了 18 名参与者,他们接受了阿斯利康 ChAdOx1-nCov-19 的异源疫苗接种方案,随后接种了 BBV152 灭活全病毒。异源组参与者在接种后没有报告任何不良反应,并表现出高体液和中和抗体应答。