Zhang Ivan L, Kratunova Evelina, Sha Amy, Marion Ian, da Fonseca Marcio A, Han Michael
Dr. Zhang is a pediatric dentist in private practice in Washington, D.C., USA.
Dr. Kratunova is clinical associate professor, Department of Pediatric Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, Ill., USA.
Pediatr Dent. 2021 Sep 15;43(5):344-348.
The purpose of this study was to compare the effectiveness of articaine local infiltration to lidocaine inferior alveolar nerve block (IANB) for restorative treatment of primary mandibular molars (PMM). Four- to 10-year-old children who needed PMM restorations were enrolled according to inclusion criteria and randomly allocated into the articaine or lidocaine group. One operator administered all local anesthesia. Using the Modified Behavioral Pain Scale (MBPS), 15 trained and calibrated examiners, blinded to LA type, evaluated the subjects' reactions during LA administration and treatment. Children rated their experience using the Wong-Baker FACES Pain Rating Scale (WBS). Subjects' blood pressure and pulse throughout the visits were recorded. Statistical analysis included independent t-tests, Mann Whitney-U, and repeated measures analysis of variance (P<0.05). Examiner reliability was determined by Cohen's kappa score. Thirty subjects (53 percent male; mean age: 6.3 years) participated. While the mean total scores for articaine (2.13 MBPS; 0.53 WBS) were better than for lidocaine (3.07 MBPS; 1.33 WBS), there were no statistically significant differences between groups. All physiological measurements were within normal limits. This pilot study indicated that articaine infiltration might be as effective as a lidocaine inferior alveolar nerve block for restorative treatment of primary mandibular molars; however, a larger sample is required to confirm these findings.
本研究的目的是比较阿替卡因局部浸润与利多卡因下牙槽神经阻滞(IANB)在乳牙下颌磨牙(PMM)修复治疗中的有效性。根据纳入标准,招募了需要进行PMM修复的4至10岁儿童,并将其随机分为阿替卡因组或利多卡因组。由一名操作人员实施所有局部麻醉。15名经过培训和校准、对局部麻醉类型不知情的检查人员使用改良行为疼痛量表(MBPS)评估受试者在局部麻醉给药和治疗过程中的反应。儿童使用面部表情疼痛评分量表(WBS)对他们的体验进行评分。记录受试者在整个就诊过程中的血压和脉搏。统计分析包括独立t检验、曼-惠特尼U检验和重复测量方差分析(P<0.05)。检查人员的可靠性通过科恩kappa评分确定。30名受试者(53%为男性;平均年龄:6.3岁)参与了研究。虽然阿替卡因的平均总分(2.13 MBPS;0.53 WBS)优于利多卡因(3.07 MBPS;1.33 WBS),但两组之间没有统计学上的显著差异。所有生理测量值均在正常范围内。这项初步研究表明,在乳牙下颌磨牙的修复治疗中,阿替卡因浸润可能与利多卡因下牙槽神经阻滞一样有效;然而,需要更大的样本量来证实这些发现。