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4%阿替卡因浸润麻醉与 2%利多卡因下牙槽神经阻滞用于下颌第一磨牙拔除的麻醉效果比较:一项前瞻性、随机对照、split-mouth 试验。

Comparative evaluation of anesthetic efficacy of 4% articaine infiltration versus 2% lignocaine inferior alveolar nerve block for extraction of primary mandibular molars: A prospective, split-mouth, randomized controlled trial.

机构信息

Department of Paediatric and Preventive Dentistry, Terna Dental College, Navi Mumbai, Maharashtra, India.

Department of Public Health Dentistry, Terna Dental College, Navi Mumbai, Maharashtra, India.

出版信息

J Indian Soc Pedod Prev Dent. 2021 Oct-Dec;39(4):409-415. doi: 10.4103/jisppd.jisppd_260_21.

DOI:10.4103/jisppd.jisppd_260_21
PMID:35102967
Abstract

CONTEXT

Control of pain during dental treatment is an essential aspect of pediatric dentistry.

AIMS

This study was conducted to evaluate and compare the anesthetic efficacy of 4% articaine buccal infiltration with 2% lignocaine inferior alveolar nerve block (IANB) for primary mandibular molar extractions.

SETTINGS AND DESIGN

The study was a prospective, split-mouth, randomized controlled trial.

METHODS

Bilateral symmetrical carious primary mandibular molar (n = 92) extractions in 46 healthy children aged 5-10 years were included in this randomized controlled trial. Extraction was performed on one side using 4% of articaine buccal infiltration and on the contralateral side using 2% lignocaine IANB in two subsequent appointments. Pain and behavior were assessed at baseline, during injection and extraction using Wong-Baker Faces Pain Rating Scale, Modified Behavior Pain Scale (MBPS), and Frankl Behavior Rating Scale.

STATISTICAL ANALYSIS USED

Values thus obtained were statistically analyzed by one-way analysis of variance test and compared using independent samples test.

RESULTS

According to MBPS, the mean value of pain experienced in the form of cry during injection was reported to be more for 2% lignocaine IANB (1.76) as compared to 4% articaine buccal infiltration (1.30), which was statistically significant (P = 0.024). Comparison of behavior depicted showed no statistically significant difference between the groups.

CONCLUSION

Buccal infiltration with 4% articaine can be utilized as an effective alternative to 2% lignocaine IANB for primary mandibular molar extractions.

摘要

背景

控制牙科治疗过程中的疼痛是儿童牙科的一个重要方面。

目的

本研究旨在评估和比较 4%阿替卡因颊侧浸润与 2%利多卡因下牙槽神经阻滞(IANB)用于下颌第一磨牙拔除的麻醉效果。

设置和设计

本研究为前瞻性、分侧、随机对照试验。

方法

纳入 46 名 5-10 岁健康儿童的双侧对称龋坏下颌第一磨牙(n=92),这些儿童参加了这项随机对照试验。一侧使用 4%阿替卡因颊侧浸润,另一侧在两次后续就诊时使用 2%利多卡因 IANB 进行拔牙。在基线、注射和拔牙时使用 Wong-Baker 面部疼痛评定量表、改良行为疼痛量表(MBPS)和 Frankl 行为评定量表评估疼痛和行为。

统计分析方法

采用单因素方差分析检验,对获得的数值进行统计学分析,并采用独立样本检验进行比较。

结果

根据 MBPS,注射时哭泣表示的疼痛平均值报告为 2%利多卡因 IANB(1.76)比 4%阿替卡因颊侧浸润(1.30)更高,具有统计学意义(P=0.024)。对行为表现的比较显示,两组之间无统计学差异。

结论

4%阿替卡因颊侧浸润可作为 2%利多卡因 IANB 用于下颌第一磨牙拔除的有效替代方法。

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