Hentsch Lisa, Stancu Patrick, Allali Gilles, Lövblad Karl-Olof, Lobrinus Johannes A, Cocetta Sara, Pautex Sophie, Uginet Marjolaine, Serratrice Jacques, Coen Matteo
Division of Palliative Medicine, Geneva University Hospitals, Geneva, Switzerland.
Division of Neurology, Department of Clinical Neuroscience, Geneva University Hospitals, Geneva, Switzerland.
Pain. 2022 Jun 1;163(6):1019-1022. doi: 10.1097/j.pain.0000000000002512. Epub 2021 Oct 11.
Many reports have described pain appearance or an increase of chronic pain concomitant to severe acute respiratory syndrome coronavirus 2 infection. Here, we describe the cases of 3 patients with chronic cancer pain, in which COVID-19 was associated with a dramatic reduction or disappearance of pain. Pain reappeared after recovery from COVID-19. Neurological imaging and pathological findings, when available, were inconclusive. To the best of our knowledge, this is the first case series reporting an acute reduction in pain perception in COVID-19. We believe further investigation is mandatory because it could shed new light on the mechanisms of pain perception and modulation.
许多报告都描述了严重急性呼吸综合征冠状病毒2感染伴有疼痛表现或慢性疼痛加剧的情况。在此，我们描述了3例慢性癌痛患者的病例，在这些病例中，新型冠状病毒肺炎（COVID-19）与疼痛显著减轻或消失相关。疼痛在从COVID-19康复后再次出现。神经影像学和病理检查结果（如有）尚无定论。据我们所知，这是首例报告COVID-19患者疼痛感知急性减轻的病例系列。我们认为有必要进行进一步调查，因为这可能为疼痛感知和调节机制提供新的线索。
