阿尔法-半乳糖综合征。对红肉和明胶过敏。
Alpha-gal syndrome. Allergy to red meat and gelatin.
机构信息
Servicio de Alergología, Hospital Sierrallana, Torrelavega, Santander, Spain.
Servicio de Alergología, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
出版信息
Rev Clin Esp (Barc). 2022 Aug-Sep;222(7):401-405. doi: 10.1016/j.rceng.2021.06.005. Epub 2021 Oct 14.
INTRODUCTION
Alpha-gal syndrome is a potentially severe food allergy caused by the presence of alpha-gal-specific IgE. The aim of this study is to describe our series of 13 patients.
MATERIAL AND METHODS
This work is a retrospective study of patients diagnosed in 2016 and 2017. Skin tests were performed with commercial extract and gelaspan as well as specific IgE determination for alpha-gal and different types of meat.
RESULTS
Thirteen patients diagnosed with alpha-gal syndrome were analyzed; 9 of them had anaphylaxis, 6 of whom had been diagnosed with idiopathic anaphylaxis. All had a positive skin test with gelaspan, though this was not true with the commercial extracts, whose results were less conclusive.
CONCLUSIONS
We believe that a diagnosis of idiopathic anaphylaxis may prevent the identification of patients with alpha-gal syndrome. The gelaspan skin test is more useful than commercial extracts.
简介
α-半乳糖综合征是一种潜在的严重食物过敏，由α-半乳糖特异性 IgE 引起。本研究的目的是描述我们的 13 例患者系列。
材料和方法
这是一项对 2016 年和 2017 年诊断的患者进行的回顾性研究。使用商业提取物和凝胶莎帕进行皮肤测试，以及针对α-半乳糖和不同类型肉类的特异性 IgE 测定。
结果
分析了 13 例诊断为α-半乳糖综合征的患者；其中 9 例发生过敏反应，其中 6 例被诊断为特发性过敏反应。所有患者的凝胶莎帕皮肤试验均为阳性，但商业提取物的结果不那么确定，并非如此。
结论
我们认为特发性过敏反应的诊断可能会阻止患者被诊断为α-半乳糖综合征。凝胶莎帕皮肤试验比商业提取物更有用。
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