University of Georgia, Department of Psychology, United States.
University of Georgia, Department of Psychology, United States.
Crit Rev Oncol Hematol. 2021 Nov;167:103498. doi: 10.1016/j.critrevonc.2021.103498. Epub 2021 Oct 14.
It is critical to support adolescents and young adults (AYAs) with sickle cell disease (SCD) during transition to adult healthcare. We provide a systematic review of literature related to biopsychosocial influences on transition among AYAs with SCD. Data sources included studies published between January 2010 and May 2020. Forty-four studies were included. Biopsychosocial factors related to improved transition outcomes included older AYA age, greater disease severity, intact neurocognitive functioning, and greater pain coping skills. Financial and insurance barriers were noted. The importance of cultural considerations and provider communication were noted across two qualitative studies. Ten studies assessed efficacy of transition interventions, with 80 % resulting in improvements; however, retention in programs was low and gaps in knowledge and skills remained. Incorporation of early, ongoing assessments of transition readiness and barriers into culturally-tailored interventions aimed at improving transition outcomes is recommended. Examination of longitudinal relationships and interactions across biopsychosocial influences is needed.
支持患有镰状细胞病（SCD）的青少年和年轻人（AYAs）在向成人保健过渡期间至关重要。我们对与 SCD AYA 过渡相关的生物心理社会影响进行了系统的文献回顾。数据来源包括 2010 年 1 月至 2020 年 5 月期间发表的研究。共纳入 44 项研究。与改善过渡结果相关的生物心理社会因素包括 AYA 年龄较大、疾病严重程度较高、神经认知功能完整和疼痛应对技能较强。还注意到了财务和保险方面的障碍。两项定性研究都指出了文化因素和提供者沟通的重要性。十项研究评估了过渡干预措施的效果，其中 80%的研究结果有所改善；然而，方案的保留率较低，知识和技能仍然存在差距。建议将对过渡准备情况和障碍的早期、持续评估纳入旨在改善过渡结果的文化定制干预措施中。需要检查生物心理社会影响的纵向关系和相互作用。
