Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, China.
Innovation Institute of China Medical University, Shenyang, China.
Dig Dis. 2022;40(4):468-478. doi: 10.1159/000520025. Epub 2021 Oct 15.
Acute acalculous cholecystitis (AAC) is characterized by acute necrotizing inflammation with no calculi and is diagnosed based on imaging, intraoperative, and pathological examinations.
Although AAC has been studied clinically for a long time, it remains difficult to diagnose and treat. The pathogenesis of AAC is still not fully understood, and it is often regarded as a relatively independent clinical disease that is different from acute calculous cholecystitis (ACC). Pathological studies suggest that AAC is the manifestation of a critical systemic disease, while ACC is a local disease of the gallbladder.
Concerning the pathogenesis, diagnosis, and treatment of AAC, we reviewed the research progress of AAC, which will enhance the understanding of the early diagnosis and treatment of AAC.
急性非结石性胆囊炎(AAC)的特征为无结石存在的急性化脓性炎症,其诊断依据为影像学、术中及病理学检查。
尽管 AAC 已在临床上研究了很长时间,但仍难以诊断和治疗。AAC 的发病机制尚不完全清楚,它通常被认为是一种与急性结石性胆囊炎(ACC)不同的相对独立的临床疾病。病理研究表明,AAC 是严重全身疾病的表现,而 ACC 是胆囊的局部疾病。
本文就 AAC 的发病机制、诊断和治疗进行综述,以增进对 AAC 的早期诊断和治疗的认识。