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常复发的常染色体显性遗传多囊肾病导致的肾重复感染,肾经导管动脉栓塞术可有效预防复发。

Repetitive Refractory Renal Cyst Infection in Autosomal Dominant Polycystic Kidney Disease for which Renal Transcatheter Arterial Embolization Was Effective in Preventing Recurrence.

机构信息

Department of Nephrology, Toranomon Hospital Kajigaya, Japan.

Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.

出版信息

Intern Med. 2021;60(20):3261-3265. doi: 10.2169/internalmedicine.6974-20. Epub 2021 Oct 15.

DOI:10.2169/internalmedicine.6974-20
PMID:34657906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8580762/
Abstract

Renal cyst infection is a frequent and serious complication of autosomal dominant polycystic kidney disease (ADPKD) that is often difficult to treat and can be fatal. While nephrectomy is the standard therapy for severe refractory renal cyst infection, it can be associated with severe adverse events. We experienced a case of repetitive renal cyst infection in a 58-year-old Japanese man with ADPKD on dialysis. He underwent renal transcatheter arterial embolization (TAE) four months after the last episodes of renal cyst infection, and his renal cyst infection has not recurred since renal TAE. This case suggested that renal TAE is effective for preventing repetitive renal cyst infection.

摘要

肾囊肿感染是常染色体显性多囊肾病 (ADPKD) 的一种严重且常见的并发症,通常难以治疗,甚至可能致命。虽然肾切除术是治疗严重难治性肾囊肿感染的标准疗法,但它可能会伴随严重的不良反应。我们遇到了一名 58 岁的日本男性透析患者,他患有 ADPKD,反复发作肾囊肿感染。在最后一次肾囊肿感染发作后四个月,他接受了肾经导管动脉栓塞术 (TAE),此后他的肾囊肿感染未再复发。该病例提示肾 TAE 可有效预防肾囊肿感染的反复发作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/643c7a67654b/1349-7235-60-3261-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/7eaa7dd85571/1349-7235-60-3261-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/0ec0a3166586/1349-7235-60-3261-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/9233b14c627f/1349-7235-60-3261-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/643c7a67654b/1349-7235-60-3261-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/7eaa7dd85571/1349-7235-60-3261-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/0ec0a3166586/1349-7235-60-3261-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/9233b14c627f/1349-7235-60-3261-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d4/8580762/643c7a67654b/1349-7235-60-3261-g004.jpg

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本文引用的文献

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Cyst infection in autosomal dominant polycystic kidney disease: our experience at Toranomon Hospital and future issues.常染色体显性遗传多囊肾病的囊肿感染:我们在本院的经验及未来问题。
Clin Exp Nephrol. 2020 Sep;24(9):748-761. doi: 10.1007/s10157-020-01928-2. Epub 2020 Jul 22.
2
Epidemiology of Autosomal Dominant Polycystic Kidney Disease in Olmsted County.奥姆斯特德县常染色体显性遗传性多囊肾病的流行病学。
Clin J Am Soc Nephrol. 2020 Jan 7;15(1):69-79. doi: 10.2215/CJN.05900519. Epub 2019 Dec 2.
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Cyst infection in autosomal dominant polycystic kidney disease: penetration of meropenem into infected cysts.
常染色体显性多囊肾病中的囊肿感染:美罗培南在感染囊肿中的渗透情况。
BMC Nephrol. 2018 Oct 19;19(1):272. doi: 10.1186/s12882-018-1067-2.
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Intracystic magnetic resonance imaging in patients with autosomal dominant polycystic kidney disease: features of severe cyst infection in a case-control study.常染色体显性多囊肾病患者的囊内磁共振成像:一项病例对照研究中严重囊肿感染的特征
BMC Nephrol. 2016 Nov 9;17(1):170. doi: 10.1186/s12882-016-0381-9.
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Suitability of Patients with Autosomal Dominant Polycystic Kidney Disease for Renal Transcatheter Arterial Embolization.常染色体显性遗传性多囊肾病患者接受肾动脉导管栓塞术的适用性
J Am Soc Nephrol. 2016 Jul;27(7):2177-87. doi: 10.1681/ASN.2015010067. Epub 2015 Nov 30.
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Cyst infection in autosomal dominant polycystic kidney disease: causative microorganisms and susceptibility to lipid-soluble antibiotics.常染色体显性多囊肾病中的囊肿感染:致病微生物及对脂溶性抗生素的敏感性
Eur J Clin Microbiol Infect Dis. 2015 Jul;34(7):1369-79. doi: 10.1007/s10096-015-2361-6. Epub 2015 Apr 8.
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Clinical features of cyst infection and hemorrhage in ADPKD: new diagnostic criteria.ADPKD 中囊肿感染和出血的临床特征:新的诊断标准。
Clin Exp Nephrol. 2012 Dec;16(6):892-902. doi: 10.1007/s10157-012-0650-2. Epub 2012 Jun 13.
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Emphysematous cyst infection in autosomal dominant polycystic kidney disease.常染色体显性多囊肾病中的气肿性囊肿感染
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Positron-emission computed tomography in cyst infection diagnosis in patients with autosomal dominant polycystic kidney disease.正电子发射断层扫描在常染色体显性多囊肾病患者囊肿感染诊断中的应用。
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