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采用 Huddart-Bodenham 评分系统和双侧唇腭裂 Yardstick 评估双侧唇腭裂患者的治疗效果:系统评价。

Treatment Outcome in Bilateral Cleft lip and Palate Patients Evaluated With the Huddart-Bodenham Scoring System and the Bilateral Cleft lip and Palate Yardstick: A Systematic Review.

机构信息

School & Hospital of Stomatology, 499766Wuhan University, Wuhan, China.

Radboud University Medical Center, 6034Radboud University, Nijmegen, the Netherlands.

出版信息

Cleft Palate Craniofac J. 2022 Nov;59(11):1377-1390. doi: 10.1177/10556656211041883. Epub 2021 Oct 18.

Abstract

OBJECTIVES

To assess treatment outcome (transversal and sagittal dental arch relationships) and its determinants in complete bilateral cleft lip and palate (BCLP) evaluated with the modified Huddart-Bodenham scoring system and the BCLP Yardstick.

MATERIALS AND METHODS

Multiple electronic databases were searched without time limitation. Randomized clinical trials, cohort and case control studies using BCLP Yardstick and/or modified Huddart-Bodenham system to judge treatment outcome of patients with BCLP were included. The Risk of Bias in Nonrandomized Studies of Interventions tool and Grading of Recommendations, Assessment, Development, and Evaluation was used.

RESULTS

Of the 528 studies identified by the electronic search, only eight retrospective studies met the inclusion criteria and were included. A total of 12 cleft centers were represented. All treatment protocols differed and background information was underreported. The results for the BCLP yardstick showed that all except the centers in New Zealand had a mean score lower than 3, indicating good treatment results. However, these studies had a moderate to high risk of bias. The modified Huddart-Bodenham scores were negative in all studies. No further meta-analysis was done due to heterogeneity and high risk of bias. The quality of evidence was graded as very low.

CONCLUSION

Results for the dental arch relationship of studies in complete BCLP and possible determinants were not synthesized due to very low quality of evidence. Clinical research for patients with BCLP should focus on sound methodological designs to enable evidence-based decision making to improve treatment for patients with BCLP and thereby hopefully their quality of life.

摘要

目的

使用改良的 Huddart-Bodenham 评分系统和 BCLP 量规评估完全性双侧唇腭裂(BCLP)的治疗结果(横向和矢状牙弓关系)及其决定因素。

材料和方法

无时间限制地搜索多个电子数据库。纳入使用 BCLP 量规和/或改良 Huddart-Bodenham 系统判断 BCLP 患者治疗结果的随机临床试验、队列研究和病例对照研究。使用非随机干预研究风险偏倚工具和推荐评估、发展与评估分级进行评估。

结果

通过电子搜索确定的 528 项研究中,只有 8 项回顾性研究符合纳入标准并被纳入。共有 12 个腭裂中心参与研究。所有治疗方案均存在差异,背景信息报告不足。BCLP 量规的结果显示,除新西兰的中心外,所有中心的平均得分均低于 3,表明治疗效果良好。然而,这些研究存在中度至高度的偏倚风险。所有研究的改良 Huddart-Bodenham 评分均为负值。由于存在异质性和高偏倚风险,未进行进一步的荟萃分析。证据质量等级为极低。

结论

由于证据质量极低,无法对完全性 BCLP 研究的牙弓关系和可能的决定因素进行综合分析。BCLP 患者的临床研究应侧重于健全的方法学设计,以便能够基于证据做出决策,从而改善 BCLP 患者的治疗效果,进而有望提高其生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf8/9537448/a8f1f8260c8e/10.1177_10556656211041883-fig1.jpg

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