抗肾小球基底膜病伴严重肾病综合征：新病例报告。
Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report.
机构信息
Department of Nephrology, Dialysis and Kidney Transplantation, La Rabta Hospital, Tunis, Tunisia.
Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
出版信息
Pan Afr Med J. 2021 Aug 16;39:243. doi: 10.11604/pamj.2021.39.243.30461. eCollection 2021.
Anti-glomerular basement membrane (anti-GBM) disease was usually described as a small vessel vasculitis presenting with acute kidney injury, haematuria and non-nephrotic proteinuria. We report a case of anti-GBM disease revealed by an intense nephrotic syndrome. The urinary protein level was 12g/day. Renal biopsy only showed crescent glomerulonephritis with linear staining of IgG in direct immunofluorescence without other glomerulonephritis. Immunoglobulin G (IgG) anti-GBM antibody titer was elevated.
抗肾小球基底膜（anti-GBM）病通常被描述为一种小血管血管炎，表现为急性肾损伤、血尿和非肾病性蛋白尿。我们报告一例由严重肾病综合征表现的抗肾小球基底膜病。尿蛋白水平为 12g/天。肾活检仅显示新月体性肾小球肾炎，直接免疫荧光法显示 IgG 线状染色，无其他肾小球肾炎。免疫球蛋白 G（IgG）抗肾小球基底膜抗体滴度升高。
Zotero 插件