Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Biomed Res Int. 2021 Oct 7;2021:9476013. doi: 10.1155/2021/9476013. eCollection 2021.
This study is aimed at synthesizing the available evidence regarding effectiveness of various modalities (combinations of LRS tasks) and comparison between each two modalities in terms of gingival display reduction, success rate, stability of the results, patient's satisfaction, and postoperative morbidity.
The electronic databases including PubMed, Scopus, Web of Science Cochrane Library, Google Scholar databases, ClinicalTrials.gov, and WHO International Clinical Trial Registry Platform were searched up to 27th June 2020 regarding lip repositioning surgery. The modalities were defined as the combinations of the following tasks: frenectomy (yes/no), flap thickness (full/partial), and myotomy (yes/no). Meta-analyses were performed on gingival display change from baseline to months 3, 6, and 12 in each modalities using Stata (v.16).
38 studies (including three clinical trials, two quasiexperimental studies, seven case series, and 26 case reports) met the criteria for final inclusion. The mean gingival display reduced from baseline to 6 months (WMD = -2.90, 95% CI: -4.85 to -0.95) in the patients undergoing the "frenectomy + full-thickness flap + myotomy" modality. This parameter decreased from baseline to 6 and 12 months, respectively (WMD = -2.68, 95% CI: -3.49 to -1.86; WMD = -2.52, 95% CI: -4.40 to -0.64), in patients undergoing the "frenectomy + partial-thickness flap + without myotomy" modality. In patients who undergone the "without frenectomy + partial-thickness flap + without myotomy" modality, gingival display reduced from baseline to 6 months (WMD = -3.22, 95% CI: -5.61 to -0.84). Almost 83% of patients with modality 1 had satisfaction.
Gingival display within the 6 months after LRS could be reduced with all modalities. Descriptively, the greatest reduction was observed in patients with the modality not including the frenulum.
本研究旨在综合现有关于各种方法（LRS 任务的组合）有效性的证据，并比较每种两种方法在减少牙龈暴露、成功率、结果稳定性、患者满意度和术后发病率方面的差异。
截至 2020 年 6 月 27 日，我们在电子数据库（PubMed、Scopus、Web of Science Cochrane Library、Google Scholar 数据库、ClinicalTrials.gov 和世界卫生组织国际临床试验注册平台）中搜索了有关唇复位手术的文献。这些方法被定义为以下任务的组合：系带切除术（有/无）、皮瓣厚度（全/部分）和肌切开术（有/无）。使用 Stata（v.16）对每种方法从基线到第 3、6 和 12 个月的牙龈暴露变化进行了 meta 分析。
38 项研究（包括三项临床试验、两项准实验研究、七项病例系列研究和 26 项病例报告）符合最终纳入标准。在接受“系带切除术+全厚皮瓣+肌切开术”方法的患者中，牙龈暴露从基线到 6 个月（WMD=-2.90，95%CI：-4.85 至-0.95）的均值降低。在接受“系带切除术+部分厚度皮瓣+无肌切开术”方法的患者中，该参数从基线到 6 个月和 12 个月分别降低（WMD=-2.68，95%CI：-3.49 至-1.86；WMD=-2.52，95%CI：-4.40 至-0.64）。在接受“无系带切除术+部分厚度皮瓣+无肌切开术”方法的患者中，牙龈暴露从基线到 6 个月（WMD=-3.22，95%CI：-5.61 至-0.84）。大约 83%的患者对模式 1 感到满意。
LRS 后 6 个月内，所有方法均可减少牙龈暴露。从描述性上看，未包含系带的患者的牙龈暴露减少最大。
