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急性粒单核细胞白血病患者的肾粒细胞肉瘤。病例报告。

Granulocytic sarcoma of the kidney in a patient with acute myelomonocytic leukaemia. A case report.

作者信息

Klein B, Falkson G, Simson I W, Stevens K, de Villiers F J, Keogan P G, Thatcher C J

出版信息

S Afr Med J. 1986 Nov 22;70(11):696-8.

PMID:3466372
Abstract

A 26-year-old man with acute myelomonocytic leukaemia had been in remission for 16 months when he developed a painful swelling of the right testis. Intravenous pyelography showed a non-functioning right kidney. Surgical exploration revealed a granulocytic sarcoma of the right kidney and a right nephrectomy was performed. The patient refused further treatment and relapsed 3 months after the nephrectomy. Autopsy revealed a large greyish-white tumour mass occupying the pelvis and retroperitoneal tissue. Special techniques with immunoperoxidase and naphthol-ASD chloro-acetate esterase staining confirmed the histological diagnosis of granulocytic sarcoma. The literature is reviewed and the rarity of this case is discussed.

摘要

一名26岁的急性粒单核细胞白血病男性患者,在缓解16个月后,右侧睾丸出现疼痛性肿胀。静脉肾盂造影显示右肾无功能。手术探查发现右肾粒细胞肉瘤,并进行了右肾切除术。患者拒绝进一步治疗,肾切除术后3个月复发。尸检发现一个巨大的灰白色肿瘤块占据盆腔和腹膜后组织。免疫过氧化物酶和萘酚-ASD氯乙酸酯酶染色等特殊技术证实了粒细胞肉瘤的组织学诊断。本文回顾了相关文献并讨论了该病例的罕见性。

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