Boeken Udo, Ensminger Stephan, Assmann Alexander, Schmid Christof, Werdan Karl, Michels Guido, Miera Oliver, Schmidt Florian, Klotz Stefan, Starck Christoph, Pilarczyk Kevin, Rastan Ardawan, Burckhardt Marion, Nothacker Monika, Muellenbach Ralf, Zausig York, Haake Nils, Groesdonk Heinrich, Ferrari Markus, Buerke Michael, Hennersdorf Marcus, Rosenberg Mark, Schaible Thomas, Köditz Harald, Kluge Stefan, Janssens Uwe, Lubnow Matthias, Flemmer Andreas, Herber-Jonat Susanne, Wessel Lucas, Buchwald Dirk, Maier Sven, Krüger Lars, Fründ Andreas, Jaksties Rolf, Fischer Stefan, Wiebe Karsten, Hartog Christiane, Dzemali Omer, Zimpfer Daniel, Ruttmann-Ulmer Elfriede, Schlensak Christian, Kelm Malte, Beckmann Andreas
Department of Cardiac Surgery, Heinrich Heine University Medical School, Moorenstraße 5, 40225, Düsseldorf, Deutschland.
Department of Cardiac and Thoracic Vascular Surgery, University Hospital of Schleswig-Holstein, Lübeck, Deutschland.
Med Klin Intensivmed Notfmed. 2021 Nov;116(8):678-686. doi: 10.1007/s00063-021-00868-3.
In Germany, a remarkable increase regarding the usage of extracorporeal membrane oxygenation (ECMO) and extracorporeal life support (ECLS) systems has been observed in recent years with approximately 3000 ECLS/ECMO implantations annually since 2015. Despite the widespread use of ECLS/ECMO, evidence-based recommendations or guidelines are still lacking regarding indications, contraindications, limitations and management of ECMO/ECLS patients. Therefore in 2015, the German Society of Thoracic and Cardiovascular Surgery (GSTCVS) registered the multidisciplinary S3 guideline "Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure" to develop evidence-based recommendations for ECMO/ECLS systems according to the requirements of the Association of the Scientific Medical Societies in Germany (AWMF). Although the clinical application of ECMO/ECLS represents the main focus, the presented guideline also addresses structural and economic issues. Experts from 17 German, Austrian and Swiss scientific societies and a patients' organization, guided by the GSTCVS, completed the project in February 2021. In this report, we present a summary of the methodological concept and tables displaying the recommendations for each chapter of the guideline.
近年来,德国体外膜肺氧合(ECMO)和体外生命支持(ECLS)系统的使用显著增加,自2015年以来,每年约有3000例ECLS/ECMO植入手术。尽管ECLS/ECMO得到了广泛应用,但在ECMO/ECLS患者的适应症、禁忌症、局限性和管理方面,仍缺乏循证医学推荐或指南。因此,2015年,德国胸心血管外科学会(GSTCVS)登记了多学科S3指南“体外循环(ECLS/ECMO)用于心脏和循环衰竭”,以根据德国科学医学协会联合会(AWMF)的要求,为ECMO/ECLS系统制定循证医学推荐。尽管ECMO/ECLS的临床应用是主要重点,但本指南也涉及结构和经济问题。在GSTCVS的指导下,来自17个德国、奥地利和瑞士科学协会以及一个患者组织的专家于2021年2月完成了该项目。在本报告中,我们总结了该指南各章节的方法学概念和推荐表格。