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Reply to "Caution in underrepresentation of older adults in clinical trials on COVID-19 vaccines".

作者信息

Veronese Nicola, Petrovic Mirko, Benetos Athanase, Denkinger Michael, Gudmundsson Adalsteinn, Knol Wilma, Marking Christine, Soulis George, Maggi Stefania, Cherubini Antonio

机构信息

Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.

Section of Geriatrics, Department of Internal Medicine and Paediatrics, Ghent University, Ghent, Belgium.

出版信息

Ageing Res Rev. 2021 Dec;72:101490. doi: 10.1016/j.arr.2021.101490. Epub 2021 Oct 17.

DOI:10.1016/j.arr.2021.101490
PMID:34670153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8520503/
Abstract
摘要

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本文引用的文献

1
Underrepresentation of older adults in clinical trials on COVID-19 vaccines: A systematic review.COVID-19 疫苗临床试验中老年人代表性不足：一项系统评价。
Ageing Res Rev. 2021 Nov;71:101455. doi: 10.1016/j.arr.2021.101455. Epub 2021 Sep 3.
2
Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial.一项在 18-59 岁健康成年人中进行的新型冠状病毒灭活疫苗的安全性、耐受性和免疫原性的随机、双盲、安慰剂对照、1/2 期临床试验。
Lancet Infect Dis. 2021 Feb;21(2):181-192. doi: 10.1016/S1473-3099(20)30843-4. Epub 2020 Nov 17.
3
Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial.一种灭活的严重急性呼吸综合征冠状病毒 2 疫苗（BBIBP-CorV）的安全性和免疫原性：一项随机、双盲、安慰剂对照、1/2 期临床试验。
Lancet Infect Dis. 2021 Jan;21(1):39-51. doi: 10.1016/S1473-3099(20)30831-8. Epub 2020 Oct 15.
4
Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes: Interim Analysis of 2 Randomized Clinical Trials.新型冠状病毒灭活疫苗在安全性和免疫原性方面的效果：两项随机临床试验的中期分析。
JAMA. 2020 Sep 8;324(10):951-960. doi: 10.1001/jama.2020.15543.
5
Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial.重组 5 型腺病毒载体 COVID-19 疫苗在 18 岁及以上健康成年人中的免疫原性和安全性：一项随机、双盲、安慰剂对照、2 期临床试验。
Lancet. 2020 Aug 15;396(10249):479-488. doi: 10.1016/S0140-6736(20)31605-6. Epub 2020 Jul 20.