Hao Lu, Sun Xing-Guo, Song Ya, Liu Fang, Tai Wen-Qi, Ge Wan-Gang, Li Hao, Zhang Ye, Chen Rong, Zou Yu-Xin, Ma Ming-Xin, Xia Rui, Huang Yan, Xie You-Hong
Fuwai Hospital,Chinese Academy of Medical Sciences/National Center for Cardiovascular Diseases/ State Key Laboratory of Cardiovascular Diseases/Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing 100037.
Henan Provincial People's Hospital,Henan 450003.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2021 Mar;37(2):120-124. doi: 10.12047/j.cjap.0084.2021.114.
To observe the effect of healthy volunteers different work rate increasing rate cardiopulmonary exercise testing (CPET) on the sub-peak parameters . Twelve healthy volunteers were randomly assigned to a moderate (30 W/min), a relatively low (10 W/min) and relatively high (60 W/min) three different work rate increasing rate CPET on different working days in a week. The core indicators related to CPET sub-peak exercise of 12 volunteers were compared according to standard Methods: anaerobic threshold (AT), oxygen uptake per unit power (ΔVO/ΔWR), oxygen uptake eficiency plateau,(OUEP), the lowest average of 90 s of carbon dioxide ventilation equivalent (Lowest VE/ VCO), the slope of carbon dioxide ventilation equivalent (VE/ VCO Slope) and intercept and anaerobic threshold oxygen uptake ventilation efficiency value (VO/ VE@AT) and the anaerobic threshold carbon dioxide ventilation equivalent value (VE/ VCO@AT). Paired t test was performed on the difference of each parameter in the three groups of different work rate increasing rate. Compared with the relatively low and relatively high work rate increasing rate group, the moderate work rate increasing rate group uptake eficiency plateau, (42.22±4.76 vs 39.54±3.30 vs 39.29±4.29) and the lowest average of 90 s of carbon dioxide ventilation equivalent (24.13±2.88 vs 25.60±2.08 vs 26.06±3.05) was significantly better, and the difference was statistically significant (P<0.05); Compared with the moderate work rate increasing rate group, the oxygen uptake per unit work rate of the relatively low and relatively high work rate increasing rate group increased and decreased significantly ((8.45±0.66 vs 10.04±0.58 vs 7.16±0.60) ml/(min·kg)), difference of which was statistically significant (P<0.05); the anaerobic threshold did not change significantly ((0.87±0.19 vs 0.87±0.19 vs 0.89±0.19) L/min), the difference was not statistically significant (P>0.05). Relatively low and relatively high power increase rate can significantly change the CPET sub-peak sports related indicators such as the effectiveness of oxygen uptake ventilation, the effectiveness of carbon dioxide exhaust ventilation, and the oxygen uptake per unit work rate. Compared with the moderate work rate increasing rate CPET, the lower and higher work rate increasing rate significantly reduces the effectiveness of oxygen uptake ventilation and the effectiveness of carbon dioxide exhaust ventilation in healthy individuals. The standardized operation of CPET requires the selection of a work rate increasing rate suitable for the subject, so that the CPET sub-peak related indicators can best reflect the true functional state of the subject.
观察健康志愿者不同工作率增加速率的心肺运动试验(CPET)对亚极量参数的影响。将12名健康志愿者随机分为中等(30W/min)、相对较低(10W/min)和相对较高(60W/min)三种不同工作率增加速率的CPET组,于一周内不同工作日进行测试。按照标准方法比较12名志愿者CPET亚极量运动的核心指标:无氧阈(AT)、单位功率摄氧量(ΔVO/ΔWR)、摄氧效率平台(OUEP)、90秒最低平均二氧化碳通气当量(最低VE/VCO)、二氧化碳通气当量斜率(VE/VCO Slope)及截距、无氧阈摄氧通气效率值(VO/VE@AT)和无氧阈二氧化碳通气当量值(VE/VCO@AT)。对三组不同工作率增加速率各参数的差异进行配对t检验。与相对较低和相对较高工作率增加速率组相比,中等工作率增加速率组的摄氧效率平台(42.22±4.76 vs 39.54±3.30 vs 39.29±4.29)和90秒最低平均二氧化碳通气当量(24.13±2.88 vs 25.60±2.08 vs 26.06±3.05)明显更好,差异有统计学意义(P<0.05);与中等工作率增加速率组相比,相对较低和相对较高工作率增加速率组的单位工作率摄氧量显著增加和降低((8.45±0.66 vs 10.04±0.58 vs 7.16±0.60)ml/(min·kg)),差异有统计学意义(P<0.05);无氧阈无明显变化((0.87±0.19 vs 0.87±0.19 vs 0.89±0.19)L/min),差异无统计学意义(P>0.05)。相对较低和相对较高的功率增加速率可显著改变CPET亚极量运动相关指标,如摄氧通气有效性、二氧化碳排出通气有效性及单位工作率摄氧量。与中等工作率增加速率的CPET相比,较低和较高工作率增加速率显著降低了健康个体的摄氧通气有效性和二氧化碳排出通气有效性。CPET的标准化操作需要选择适合受试者的工作率增加速率,以使CPET亚极量相关指标能最佳反映受试者的真实功能状态。