COVID-19 大流行期间 2 型糖尿病患者糖化血红蛋白水平的年度变化趋势。
Year-Long Trend in Glycated Hemoglobin Levels in Patients with Type 2 Diabetes during the COVID-19 Pandemic.
机构信息
Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Center of Biostatistics, School of Medicine, Kyungpook National University, Daegu, Korea.
出版信息
Endocrinol Metab (Seoul). 2021 Oct;36(5):1142-1146. doi: 10.3803/EnM.2021.1154. Epub 2021 Oct 21.
It has been suggested that the coronavirus disease 2019 (COVID-19) pandemic has had a negative impact on glycemic control in patients with type 2 diabetes mellitus (T2DM). However, no study has examined yearly trends in glycated hemoglobin (HbA1c) levels after the start of the COVID-19 outbreak. Here, we performed a retrospective analysis of HbA1c concentrations during the early period of the COVID-19 outbreak (COVID-19 cohort) and then compared the yearly trend in the mean HbA1c level, along with fluctuations in HbA1c levels, with those during previous years (non-COVID-19 cohorts). We observed that the mean HbA1c level in patients with T2DM increased during the first 6 months of the COVID-19 outbreak. After 6 months, HbA1c levels in the COVID-19 cohort returned to levels seen in the non-COVID-19 cohorts. The data suggest that vulnerable patients with T2DM should be monitored closely during the early period of a pandemic to ensure they receive appropriate care.
有人认为，2019 年冠状病毒病（COVID-19）大流行对 2 型糖尿病（T2DM）患者的血糖控制产生了负面影响。然而，尚无研究检测 COVID-19 爆发开始后糖化血红蛋白（HbA1c）水平的年度变化趋势。在这里，我们对 COVID-19 爆发早期的 HbA1c 浓度进行了回顾性分析（COVID-19 队列），然后将平均 HbA1c 水平的年度变化趋势以及 HbA1c 水平的波动与前几年（非 COVID-19 队列）进行了比较。我们观察到，在 COVID-19 大流行的前 6 个月，T2DM 患者的平均 HbA1c 水平升高。6 个月后，COVID-19 队列中的 HbA1c 水平恢复到非 COVID-19 队列中的水平。这些数据表明，在大流行的早期，脆弱的 T2DM 患者应密切监测，以确保他们得到适当的护理。
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