Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Kobe, Japan.
Center for Diabetes, Endocrinology and Metabolism, Kansai Electric Power Hospital, Osaka, Japan.
J Diabetes Investig. 2021 Sep;12(9):1718-1722. doi: 10.1111/jdi.13526. Epub 2021 Mar 10.
To clarify the association between lifestyle changes as a result of coronavirus disease 2019 containment measures and changes in metabolic and glycemic status in patients with diabetes, a cross-sectional, single-center, observation study was carried out. A self-reported questionnaire was provided to ascertain the frequency of various lifestyle activities before and after the coronavirus disease 2019 containment measures in Japan. Among 463 patients, change in glycated hemoglobin was significantly associated with change in bodyweight. After stratification by age 65 years, binary logistic regression analysis showed that increased frequency of snack eating increased bodyweight (odds ratio 1.709, P = 0.007) and glycated hemoglobin (odds ratio 1.420, P = 0.025) in the younger group, whereas in the older patients, reduced walking activities resulted in weight gain (odds ratio 0.726, P = 0.010). In conclusion, changes in eating behavior and physical activity increased bodyweight and reduced glycemic control among diabetes patients, but by different processes depending on age under the coronavirus disease 2019 containment measures in Japan.
为了阐明 2019 冠状病毒病(COVID-19)遏制措施导致的生活方式改变与糖尿病患者代谢和血糖状态变化之间的关系,开展了一项横断面、单中心、观察性研究。提供了一份自我报告问卷,以确定日本 COVID-19 遏制措施前后各种生活方式活动的频率。在 463 名患者中,糖化血红蛋白的变化与体重变化显著相关。按年龄 65 岁分层后,二元逻辑回归分析显示,零食进食频率增加与体重增加(比值比 1.709,P=0.007)和糖化血红蛋白升高(比值比 1.420,P=0.025)相关,而在老年患者中,步行活动减少导致体重增加(比值比 0.726,P=0.010)。总之,在日本 COVID-19 遏制措施下,饮食行为和体力活动的改变增加了糖尿病患者的体重,并降低了血糖控制水平,但这一过程因年龄而异。