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新加坡中年女性的性生活不活跃和性功能障碍:一项前瞻性横断面研究的流行率和危险因素。

Sexual inactivity and sexual dysfunction in midlife Singaporean women: A prospective cross-sectional study of prevalence and risk factors.

机构信息

Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, 119228, Singapore; NUS Yong Loo Lin School of Medicine, National University of Singapore, 19228, Singapore.

Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, 119228, Singapore.

出版信息

Maturitas. 2021 Oct;152:1-9. doi: 10.1016/j.maturitas.2021.07.002. Epub 2021 Jul 9.

Abstract

OBJECTIVES

To examine factors relating to both sexual inactivity and sexual dysfunction in midlife Singaporean women.

STUDY DESIGN

Sociodemographic, medical/lifestyle factors, physical activity, BMI, handgrip strength (HGS) and physical performance data collected from healthy Chinese, Indian, and Malay women, aged 45-69 years, attending gynaecology clinics.

MAIN OUTCOME MEASURES

Sexual inactivity and sexual dysfunction (defined as total score ≤ 26.55) assessed using the Female Sexual Function Index (FSFI).

RESULTS

1048 women completed the FSFI. Mean (±SD) age was 56.2 (±6.2). Sexual inactivity was reported by 43.2% and was positively associated with older age [55-64 years (aOR 2.0, 95% CI 1.3-3.0) and ≥65 years (aOR 2.5, 95% CI 1.2-5.1)], younger menarche (aOR 1.8, 95% CI 1.3-2.5), lowest education (aOR 2.1, 95% CI 1.2-3.6), lowest income (aOR 1.8, 95% CI 1.1-2.8), unmarried (aOR 4.0, 95% CI 2.6-6.4), nulliparity (aOR 1.9, 95% CI 1.1-3.4), and BMI <18.5 kg/m (aOR 2.7, 95% CI 1.3-5.6). Among the sexually active, sexual dysfunction was identified in 70.3%. Sexual dysfunction was positively associated with menopause ≥10 years (aOR 2.4, 95% CI 1.1-5.0), nulliparity (aOR 3.0, 95% CI 1.1-9.8), moderate/severe vaginal dryness (aOR 13.8, 95% CI 4.8-38.7) and HGS <18 kg (aOR 1.9, 95% CI 1.1-3.2) and negatively associated with use of menopausal hormone therapy (aOR 0.3, 95% CI 0.1-0.6).

CONCLUSION

This, the largest Singaporean sexual function study, is the first to include physical performance in a healthy population. Most were sexually active but reported dysfunction. Novel associations included underweight BMI with sexual inactivity and weaker HGS and Malay ethnicity with greater and less sexual dysfunction, respectively.

摘要

目的

探讨与中年新加坡女性性行为不活跃和性功能障碍相关的因素。

研究设计

从中年 45-69 岁参加妇科诊所的华裔、印裔和马来裔健康女性中收集社会人口统计学、医学/生活方式因素、身体活动、BMI、握力(HGS)和身体表现数据。

主要观察指标

使用女性性功能指数(FSFI)评估性行为不活跃和性功能障碍(定义为总分≤26.55)。

结果

1048 名女性完成了 FSFI。平均(±SD)年龄为 56.2(±6.2)岁。43.2%的女性报告性行为不活跃,且与年龄较大(55-64 岁(优势比 2.0,95%置信区间 1.3-3.0)和≥65 岁(优势比 2.5,95%置信区间 1.2-5.1))、月经初潮较晚(优势比 1.8,95%置信区间 1.3-2.5)、受教育程度最低(优势比 2.1,95%置信区间 1.2-3.6)、收入最低(优势比 1.8,95%置信区间 1.1-2.8)、未婚(优势比 4.0,95%置信区间 2.6-6.4)、未生育(优势比 1.9,95%置信区间 1.1-3.4)和 BMI<18.5kg/m(优势比 2.7,95%置信区间 1.3-5.6)有关。在性行为活跃的女性中,70.3%的女性存在性功能障碍。性功能障碍与绝经≥10 年(优势比 2.4,95%置信区间 1.1-5.0)、未生育(优势比 3.0,95%置信区间 1.1-9.8)、中度/重度阴道干燥(优势比 13.8,95%置信区间 4.8-38.7)和 HGS<18kg(优势比 1.9,95%置信区间 1.1-3.2)呈正相关,与使用绝经激素治疗呈负相关(优势比 0.3,95%置信区间 0.1-0.6)。

结论

这是新加坡最大的性功能研究,首次在健康人群中纳入了身体表现。大多数女性都有性行为,但报告存在性功能障碍。新的关联包括低 BMI 与性行为不活跃以及较弱的 HGS 和马来族裔与更大和更小的性功能障碍有关。

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