Moulton B C, Koenig B B
Ann N Y Acad Sci. 1986;476:95-109. doi: 10.1111/j.1749-6632.1986.tb20925.x.
In our discussion of responses of the uterine epithelium to the blastocyst and their relationship to sensitization to deciduogenic stimuli, we have attempted to identify pieces of information that could be arranged into possible mechanisms. These choices and the limits of space resulted in a great deal of information that was not mentioned: changes in the charge and composition of the glycocalyx of the luminal epithelium, the morphology of the apical surface of the epithelium, steroid hormone receptor levels, epithelial protein synthesis, and most of the information obtained from species other than rats and mice. Despite whatever distortion that may have resulted from our reductions and simplifications of the mechanisms of implantation, it should be clear that blastocyst implantation involves communication not only between blastocyst and uterus, but also between various uterine tissues. Our understanding of implantation will be improved if we can identify the responses of individual tissues and the mechanisms of this communication. It seems likely that development and loss of uterine sensitivity controlled by progesterone and estradiol will depend upon separate biochemical responses in specific uterine tissues.
在我们对子宫上皮对胚泡的反应及其与蜕膜化刺激致敏关系的讨论中，我们试图找出可整理成可能机制的信息片段。这些选择以及篇幅限制导致大量信息未被提及：腔上皮糖萼的电荷和组成变化、上皮顶端表面的形态、类固醇激素受体水平、上皮蛋白合成，以及从大鼠和小鼠以外的物种获得的大部分信息。尽管我们对植入机制的简化和缩减可能导致了一些歪曲，但应该清楚的是，胚泡植入不仅涉及胚泡与子宫之间的交流，还涉及各种子宫组织之间的交流。如果我们能够确定各个组织的反应以及这种交流的机制，我们对植入的理解将会得到改善。似乎由孕酮和雌二醇控制的子宫敏感性的发展和丧失将取决于特定子宫组织中不同的生化反应。
