Zhang Zhen, Li Anni, Zhao Beibei, Li Pinhua, Wang Lei, Miao Tao
Department of Chemistry; Key Laboratory of Green and Precise Synthetic Chemistry, Ministry of Education, Huaibei Normal University, Huaibei, Anhui 235000, P. R. China.
Advanced Research Institute and Department of Chemistry, Taizhou University, Taizhou, Zhejiang 318000, P. R. China.
Org Lett. 2021 Nov 5;23(21):8204-8208. doi: 10.1021/acs.orglett.1c02942. Epub 2021 Oct 22.
A novel and efficient method for the selective synthesis of sulfinylated benzofulvenes has been developed through the BF·EtO-promoted electrophilic addition/cyclization of 1,3-enynes. This metal-free cascade reaction employs readily accessible arylsulfinic acids as sulfinyl cation sources at room temperature and provides a wide range of functionalized benzofulvenes in good to excellent yields under mild conditions.
通过BF·EtO促进的1,3-烯炔的亲电加成/环化反应，开发了一种新颖、高效的选择性合成亚磺酰化苯并富烯的方法。这种无金属的串联反应在室温下使用易于获得的芳基亚磺酸作为亚磺酰阳离子源，在温和条件下以良好至优异的产率提供了多种功能化的苯并富烯。
